Abstract:Ever since its invention, solid phase microextraction (SPME) has been widely used for aqueous sampling. In recent years, this technique has received increasing attention for the analysis of complex water sample because of its capability of sensing freely dissolved analytes in the complex matrix. In this chapter, the development of negligible depletion SPME (nd-SPME) for the determination of freely dissolved analytes in complex water samples is reviewed. The fundamentals and sampling conditions of nd-SPME are f… Show more
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