Solid-Phase Extraction at High pH as a Promising Tool for Targeted Isolation of Biologically Active Fractions of Humic Acids
Tatiana A. Mikhnevich,
Vitaly G. Grigorenko,
Maya Yu. Rubtsova
et al.
Abstract:A search for novel sources of biologically active compounds
is
at the top of the agenda for biomedical technologies. Natural humic
substances (HSs) contain a large variety of different chemotypes,
such as condensed tannins, hydrolyzable tannins, terpenoids, lignins,
etc. The goal of this work was to develop an efficient separation
technique based on solid-phase extraction (SPE) for the isolation
of narrow fractions of HS with higher biological activity compared
to the initial material. We used lignite humic ac… Show more
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