Solid Oral Dosage Forms Use in Adults with Neurological Disorders and Swallowing Difficulties: A Scoping Review

Neto, Carolina Justus Buhrer Ferreira; Andrade, Rayza Assis de; Tonin, Fernanda S.; Wiens, Astrid

doi:10.1007/s00455-021-10352-x

Cited by 6 publications

(12 citation statements)

References 57 publications

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“…The authors found that there was subjective feelings of difficulty in swallowing medication in 73% of cases 10 . Therefore, the results of the current study, with its finding of subjective feelings of difficulty in swallowing SODFs in approximately 70% of cases, are in line with those of a previous study 10,12 …”

Section: Discussionsupporting

confidence: 93%

“…In this study, 71.0% of participants reported feelings of difficulty in taking SODFs, but most patients ingested SODFs despite this difficulty. Previous studies reported that feelings of difficulty in taking medication among patients with dysphagia ranged from 40% to 70% 10–12 . In a study on patients with neuromuscular disease conducted by Nozaki et al., they were asked a number of interview questions.…”

Section: Discussionmentioning

confidence: 99%

“…Previous studies reported that feelings of difficulty in taking medication among patients with dysphagia ranged from 40% to 70%. [10][11][12] In a study on patients with neuromuscular disease conducted by Nozaki et al, they were asked a number of interview questions. The authors found that there was subjective feelings of difficulty in swallowing medication in 73% of cases.…”

Section: Number Of Medicationsmentioning

confidence: 99%

“…7,11 More than 70% of patients with neurological diseases at high risk of dysphagia experience difficulty in taking their medication, both self-reportedly and objectively. 10,12 It is expected that if each of the previous studies had included more detailed symptoms, such as feeling the SODFs stuck in the throat, pharynx, or mouth, then the number of patients experiencing difficulty in taking SODFs would have increased further.…”

Section: Introductionmentioning

confidence: 99%

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Problems experienced when swallowing solid oral dosage forms in older Japanese patients with dysphagia: A cross‐sectional study

Tanaka

Kikutani

Tamura

et al. 2023

Special Care in Dentistry

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AimsWe aimed to assess the difficulty in taking solid oral dosage forms (SODFs) among older people with dysphagia and clarify the relationship between difficulty in swallowing SODFs and swallowing function.Methods and resultsOutpatients from a dysphagia clinic aged ≥65 years were asked yes‐or‐no questions about the applicability of eight items regarding difficulty in taking SODFs. Additionally, a videofluorographic swallowing study (VFSS) was performed to assess their swallowing function. The Kruskal–Wallis test and Spearman's rank correlation coefficient were used to analyze the relationship between difficulty in taking SODFs and swallowing function.ResultsAmong the 93 participants, the average number of SODFs consumed was 5.8 ± 3.1. In the questionnaire, the average number of “yes” answers was 2.2 ± 2.2, and 65 patients (71.0%) answered “yes” to at least one question. Additionally, no significant relationship was observed between the perceived difficulty in swallowing SODFs and VFSS findings.ConclusionApproximately 70% of participants reported subjective difficulty in taking SODFs, showing that patients uniformly reported perceived difficulty in taking SODFs regardless of actual swallowing function. The results of this study suggest that patients must be questioned thoroughly about their SODFs use, regardless of the objective severity of their dysphagia.

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Section: Discussionsupporting

confidence: 93%

Section: Discussionmentioning

confidence: 99%

Section: Number Of Medicationsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Problems experienced when swallowing solid oral dosage forms in older Japanese patients with dysphagia: A cross‐sectional study

Tanaka

Kikutani

Tamura

et al. 2023

Special Care in Dentistry

View full text Add to dashboard Cite

show abstract

“…In addition to the mentioned strategies, whole or modified SODFs may be concealed in liquids or food (thickened or not), oral jellies or jellified water (Bonacucina et al, 2016;Bourdenet et al, 2015;Ferreira-Neto et al, 2022;Fodil et al, 2017;Salmeron, 2018).…”

Section: Introductionmentioning

confidence: 99%

Optimization of solid oral dosage form administration to patients with swallowing difficulties: An integrative review

Ferreira‐Neto,

de Lara,

Cominato

et al. 2023

Journal of Advanced Nursing

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AimTo appraise and synthesize research investigating optimizing the administration of solid oral dosage forms (SODFs) to adults with swallowing difficulties.DesignAn integrative review.MethodsAn electronic search was conducted on Medical Literature Analysis and Retrieval System Online (Public Medline interface), Elsevier SciVerse Scopus and Scientific Electronic Library Online (updated February 2023). Restriction regarding the publication date was not considered for the inclusion of records. Studies addressing risks, general aspects, recommendations about patient postural adjustments, swallowing techniques, swallowing aids and aspects of concealment of SODFs were included.ResultsFifty‐three records published between 2002 and 2021 were included. The main administration risks were aspiration, asphyxia and solid oral dosage form‐induced oral/oesophageal mucosal lesions. The most frequent general aspect reported was administering one oral dosage form at a time. The sitting position was the most patient postural adjustment mentioned. The most frequently reported solid oral dosage form swallowing technique was the lean‐forward method for capsules. Solid oral dosage form swallowing aids cited: tongue and throat lubricant and solid oral dosage form coating device, swallowing cup and swallowing straw.ConclusionThe literature data on administering SODFs for adults with swallowing difficulties were appraised and synthesized. Some aspects, for example, not administering SODFs simultaneously, can make swallowing safer. Postural adjustments and solid oral dosage form swallowing aids are important to avoid administration risks. Swallowing SODFs can be easier if learned by techniques. Liquid and food are helpful as vehicles, and several of these have been listed.Implications for the Profession and/or Patient CareBy optimizing the contributing factors of administering oral pharmacotherapy, the nurse can use appropriate practices to improve patient safety. Additionally, knowing and establishing the administration aspects are reasonable steps for standardizing care for patients with swallowing oral dosage form difficulties.Impact This study addressed administering SODFs to adult patients with swallowing difficulties. The administration of SODFs to adult patients with swallowing difficulties can be optimized if only one oral dosage form at a time is administrated and if patient postural adjustments, swallowing techniques and swallowing aids are used. This investigation will impact the care of patients with swallowing difficulties. Reporting MethodThe authors declare they adhered to the relevant EQUATOR guidelines and report following the Preferred Reporting Items for Systematic Reviews and Meta‐Analyses (PRISMA) 2020 Statement.Patient or Public ContributionNo patient or public contribution.

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Dysphagia for medication in Parkinson’s disease

Labeit

Berkovich²,

Claus

et al. 2022

npj Parkinsons Dis.

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Dysphagia is common in Parkinson’s disease (PD) and is assumed to complicate medication intake. This study comprehensively investigates dysphagia for medication and its association with motor complications in PD. Based on a retrospective analysis, a two-dimensional and graduated classification of dysphagia for medication was introduced differentiating swallowing efficiency and swallowing safety. In a subsequent prospective study, sixty-six PD patients underwent flexible endoscopic evaluation of swallowing, which included the swallowing of 2 tablets and capsules of different sizes. Dysphagia for medication was present in nearly 70% of PD patients and predicted motor complications according to the MDS-UPDRS-part-IV in a linear regression model. Capsules tended to be swallowed more efficiently compared to tablets, irrespective of size. A score of ≥1 on the swallow-related-MDS-UPDRS-items can be considered an optimal cut-off to predict dysphagia for medication. Swallowing impairment for oral medication may predispose to motor complications.

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Solid Oral Dosage Forms Use in Adults with Neurological Disorders and Swallowing Difficulties: A Scoping Review

Cited by 6 publications

References 57 publications

Problems experienced when swallowing solid oral dosage forms in older Japanese patients with dysphagia: A cross‐sectional study

Problems experienced when swallowing solid oral dosage forms in older Japanese patients with dysphagia: A cross‐sectional study

Optimization of solid oral dosage form administration to patients with swallowing difficulties: An integrative review

Dysphagia for medication in Parkinson’s disease

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