Solid malignant metastases in the jaw bones

Rogulj, Ana Andabak; Lončarić, Čedna Tomasović; Müller, Danko; Blivajs, Igor; Andabak, Matej; Boras, Vanja Vučičević; Šekerija, Mario

doi:10.1016/j.bjoms.2018.07.013

Cited by 10 publications

(17 citation statements)

References 12 publications

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“…Finally, for the study of the incidence rate of metastases in the oral cavity, 9 clinical cases ( 5 , 7 , 8 , 14 - 19 ) and 7 retrospective studies of case series have been included in this article ( Table 1 ) ( 2 , 4 , 12 , 20 - 23 ). From 609 tumors analyzed, 236 are in women (38.7%) and 373 are in men (61.2%), with a female/male distribution ratio of 0.63:1.…”

Section: Resultsmentioning

confidence: 99%

“…From 609 tumors analyzed, 236 are in women (38.7%) and 373 are in men (61.2%), with a female/male distribution ratio of 0.63:1. In the clinical cases and case series studied, the mean age at the time of the oral metastases diagnosis is 62.1 years ( 2 , 4 , 5 , 7 , 8 , 12 , 14 - 19 , 21 - 24 ).…”

Section: Resultsmentioning

confidence: 99%

“…In healthy patients who respond properly to primary tumor therapy, aggressive treatment is recommended for oral metastases. However, if the primary tumor is recurrent and has other metastases, treatment of the oral lesion should be minimally invasive ( 11 , 12 ).…”

Section: Introductionmentioning

confidence: 99%

“…In approximately 30% of patients with metastases in the jaw, the location of the primary tumor is unknown ( 10 , 12 ). This is the reason why knowing how to identify malignant lesions in the oral cavity is of great value, taking them into account in the differential diagnosis of inflammatory and reactive lesions, which are more common in this region.…”

Section: Introductionmentioning

confidence: 99%

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Incidence rate of metastases in the oral cavity: a review of all metastatic lesions in the oral cavity

Oliver-Puigdomènech¹,

González-Navarro²,

Polis-Yanes³

et al. 2021

Med Oral

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Background Metastases in the oral cavity are rare and account for only 1 to 3% of all malignant lesions in this area. The primary location from which most metastases have been described in the oral cavity in adult patients include lungs, breasts, kidneys and colon. Material and Methods A systematic search of the literature was carried out following the PRISMA statement in PubMed database. Clinical trials and case series published in the last 10 years [2010-2020] were eligible to be selected. The headings and keywords used in the searches were “cancer” AND “oral metastases”, “incidence” AND “oral metastases”, “oral metastases” AND “jaw bone”, “oral metastases” AND “soft tissue”. Results For the study of the incidence of metastases in the oral cavity, 9 reports of clinical trials and 7 retrospective studies of case series have been included in this article. The primary locations from which more metastases have been described in the oral cavity are lungs (30.6% or 183 cases), breasts (22.2% or 133 cases), liver (15.5% or 93 cases), prostate (9 % or 54 cases), thyroid glands (8.1% or 49 cases), kidneys (7.3% or 44 cases), skin (2.3% or 14 cases), soft tissues (2% or 12 cases), colon (2% or 12 cases) and gastrointestinal (0.6% or 4 cases). These metastases have a predilection for hard tissues. The clinical presentation of these lesions varies from painless granulomatous lesions to lytic areas in the jaws. Conclusions Although metastases in the oral cavity is an uncommon pathology, early diagnosis is needed so that in the event that it is the first manifestation, it allows the primary tumor to be diagnosed as soon as possible. Key words: Cancer, oral metastases, incidence, jaw bone, soft tissue.

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Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Incidence rate of metastases in the oral cavity: a review of all metastatic lesions in the oral cavity

Oliver-Puigdomènech¹,

González-Navarro²,

Polis-Yanes³

et al. 2021

Med Oral

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“…8 Because of their rarity and atypical clinical and radiographic appearances, metastatic lesions are a diagnostic challenge. 9 Over 90% of jawbone malignancies are osteolytic, yet 5% of reported cases to the jawbones lack any radiographic change. 8 These osteolytic changes, although nonspecific, are usually radiolucent lesions with ill-defined margins, sometimes with a moth-eaten appearance that can simulate osteomyelitis, as seen with our patient.…”

Section: Discussionmentioning

confidence: 99%

Mandibular metastasis from lung adenocarcinoma as the first sign of occult malignancy

Johnson

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2020

Baylor University Medical Center Proceedings

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Metastatic disease to the oral and maxillofacial region is rare, with only about 1% of oral malignancy attributed to metastases. In approximately 20% of these patients, oral metastases are discovered before the detection of the primary tumor. Here we present a case of a 66-year-old man who presented with vague left mandibular pain and new-onset lip numbness as the first sign of occult malignancy from lung adenocarcinoma with multiple metastases.

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