Solid-liquid phase equilibrium of 2, 4-epibrassinolide in binary mixed solvents: Solubility determination, model correlation, preferential solvation and thermodynamic properties

Zhao, Jingshuai; Liu, Bao‐Shu; Zuo, Jiabao; Sun, Hua

doi:10.1016/j.jct.2023.107066

Cited by 4 publications

(2 citation statements)

References 37 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…8−10 Solubility is the mass of the solute that can be dissolved when a solution is saturated at a given temperature. By measuring the solubility data of compounds in different solvents, it is possible to facilitate the study of drug synthesis, pharmacokinetic properties, and clinical applications, 11,12 as well as homogeneous catalytic reaction rates and equilibria, among others. 13,14 Crystallization separation is a prevalent separation operation, which occupies an important position with the advantages of greenness, low energy consumption, and higher product purity.…”

Section: Introductionmentioning

confidence: 99%

“…Solubility data is one of the essential parameters of solid–liquid phase equilibrium theory and serves as the foundation for practical procedures such as compound synthesis, separation, and participation in reactions. − Solubility is the mass of the solute that can be dissolved when a solution is saturated at a given temperature. By measuring the solubility data of compounds in different solvents, it is possible to facilitate the study of drug synthesis, pharmacokinetic properties, and clinical applications, , as well as homogeneous catalytic reaction rates and equilibria, among others. , Crystallization separation is a prevalent separation operation, which occupies an important position with the advantages of greenness, low energy consumption, and higher product purity. Solubility data dictate the maximum yield of crystallization.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Determination of Solubility and Thermodynamic Analysis of Iron(III) β-Diketonate Compounds in Pure Solvents

Yang,

Ma,

et al. 2024

J. Chem. Eng. Data

View full text Add to dashboard Cite

In this work, the solubility of Fe(acac) 3 (acac = acetylacetone) in five organic solvents (n-propanol, diethyl ether, ethyl acetate, tetrahydrofuran, ethanol), Fe(acch) 3 (acch = 2-acetylcyclohexanoate) in five organic solvents (acetonitrile, diethyl ether, ethyl acetate, methyl acetate, ethanol) and Fe(ba) 3 (ba = benzoylacetone) in four organic solvents (acetonitrile, diethyl ether, ethyl acetate, methyl acetate) were determined from 268.15 to 298.15 K by static analysis. The measured results demonstrated that the solubility data increased with increasing temperature. Solubility for the complexes was related using five thermodynamic models. Among them, in terms of empirical models, the Apelblat model was broadly applicable and had an average ARD of less than 3%. The activity coefficient model (NRTL model) had a good fit effect with an average ARD of less than 1.5%. Furthermore, the molecular electrostatic potential (ESP) of iron(III) β-diketonate compounds reflected that O atoms readily formed hydrogen bonds. Hirshfeld surface analysis revealed that the largest contact rate was in the H•••H contact.

show abstract

Section: Introductionmentioning

confidence: 99%