“…Techniques for the fabrication of porous inorganic materials are well developed, and with the advent of the so-called solid-free-form fabrication technologies, or rapid prototyping technologies, we can now custom design and produce porous scaffolds directly from a computer-aided design (CAD) model with determined shapes and porosities ( Figure 5). [19] These techniques produce 3-D objects guided by a CAD file, as well as digital data produced by an imaging source such as computed tomography (CT) or magnetic resonance imaging (MRI), opening the door for the fabrication of custom-designed implants. Gradients in material porosity, as well as sequential infiltration of polymers with different resorbability, can be used to further manipulate the material resorption rate.…”