Solar insolation in springtime influences age of onset of bipolar I disorder

Bauer, Michael; Glenn, Tasha; Alda, Martin; Aleksandrovich, M. A.; Andreassen, Ole A.; Angelopoulos, Elias; Ardau, Raffaella; Ayhan, Yavuz; Baethge, Christopher; Bharathram, S. R.; Bauer, Rita; Baune, Bernhard T.; Becerra‐Palars, Claudia; Bellivier, Frank; Belmaker, Robert H.; Berk, Michael; Bersudsky, Yuly; Bicakci, Şule; Birabwa-Oketcho, Harriet; Bjella, Thomas; Bossini, Letizia; Cabrera, Jorge; Cheung, Eric Yat Wo; Zompo, Maria Del; Dodd, Seetal; Donix, Markus; Étain, Bruno; Fagiolini, Andrea; Fountoulakis, Kostas N.; Frye, Mark A.; González-Pinto, Ana; Gottlieb, John F.; Grof, Paul; Harima, Hirohiko; Henry, Chantal; Isometsä, Erkki; Janno, Sven; Kapczinski, Flávio; Kardell, Mathias; Khaldi, Slim; Kliwicki, Sebastian; König, Barbara; Kot, Timur L.; Krogh, Rikke; Kunz, Maurício; Lafer, Beny; Landén, Mikael; Larsen, Erik Roj; Lewitzka, Ute; Licht, Rasmus W; López‐Jaramillo, Carlos; MacQueen, Glenda; Manchia, Mirko; Marsh, Wendy; Martínez‐Cengotitabengoa, Mónica; Melle, Ingrid; Meza-Urzúa, Fátima; Ming, Mok Yee; Monteith, Scott; Morken, Gunnar; Mosca, Enrica; Muñoz, Rodrigo A.; Mythri, Starlin Vijay; Nacef, F.; Nadella, Ravi Kumar; Nery, Fabiano G.; Nielsen, René Ernst; O′Donovan, Claire; Omrani, Adel; Osher, Yamima; Sørensen, Helle Østermark; Ouali, Uta; Ruiz, Yolanda Pica; Pilhatsch, Maximilian; Pinna, Marco; Ponte, Francisco Diego Rabelo da; Quiroz, Danilo; Ramesar, Raj; Rasgon, Natalie; Reddy, M S; Reif, Andreas; Ritter, Philipp; Rybakowski, Janusz; Sagduyu, Kemal; Scippa, Ângela M.; Severus, Emanuel; Simhandl, Christian; Stein, Dan J.; Strejilevich, Sergio; Subramaniam, Mythily; Sulaiman, Ahmad Hatim; Suominen, Kirsi; Tagata, Hiromi; Tatebayashi, Yoshitaka; Tondo, Leonardo; Torrent, Carla; Vaaler, Arne; Veeh, Julia; Vieta, Eduard; Viswanath, Biju; Yoldi‐Negrete, María; Zetin, Mark; Zgueb, Yosra; Whybrow, Peter C.

doi:10.1111/acps.12772

Cited by 24 publications

(24 citation statements)

References 90 publications

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“…Specifically, over the last decade, a number of researchers thoroughly explored this phenomenon assuming that meteorological variations affect not only human behavior, but also the onset and course of major psychiatric disorders such as BD [12,13,15,32]. A significant link between seasonality and affective recurrences has been reported in BD.…”

Section: Discussionmentioning

confidence: 99%

“…In healthy subjects, environmental variables such as sunlight exposure, photoperiod and solar radiation/insolation can regulate behavior affecting circadian functions and detemine changes of many biological rhythms. Recently, some authors investigated the role of these factors in bipolar patients with significant impact on both the onset and course of BD and consequently on sleep-wake cycle, mood and energy [10,12,13,14,15,16]. Furthermore, certain authors indicated that environmental factors, such as humidity, day length, ultraviolet radiation, temperature, rainfall/atmospheric pressure or airborne allergens exert a significant role on the admission of BD patients, particularly in (hypo)manic phase, or when they exhibit specific symptoms such as psychosis, impulsiveness, and suicidal behavior/aggression [14,17,18,19,20,21,22,23,24,25].…”

Section: Introductionmentioning

confidence: 99%

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Maximum Temperature and Solar Radiation as Predictors of Bipolar Patient Admission in an Emergency Psychiatric Ward

Aguglia

Serafini

Escelsior

et al. 2019

IJERPH

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Environmental variables can regulate behavior in healthy subjects. Recently, some authors investigated the role of meteorological variables in bipolar patients with an impact on both the onset and course of bipolar disorder (BD). The aim of this study was to investigate the impact of meteorological variables and other indexes in bipolar hospitalized patients. We examined all patients admitted to the Psychiatric Inpatient Unit of San Luigi Gonzaga Hospital, Orbassano (Turin, Italy) from September 2013 to August 2015, collecting several socio-demographic and clinical characteristics. Seven hundred and thirty patients were included. Compared to the day of admission of control individuals, patients with BD were admitted on a day that presented higher minimum, medium, and maximum temperature, higher maximum humidity, higher solar radiation, and higher hours of sunshine. After logistic regression analysis, admissions to the emergency psychiatric ward due to a primary diagnosis of BD were associated with maximum temperature and solar radiation. The current study provides a novel perspective on the question surrounding seasonal mood patterns in patients with BD. A greater awareness of all possible precipitating factors is needed to inform self-management and psycho-educational programs as well as to improve resilience regarding affective recurrences in the clinical practice.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Maximum Temperature and Solar Radiation as Predictors of Bipolar Patient Admission in an Emergency Psychiatric Ward

Aguglia

Serafini

Escelsior

et al. 2019

IJERPH

View full text Add to dashboard Cite

show abstract

“…Additional findings entailing climate variables include the observed association between hospital admissions for bipolar depression and temperature (19), as well as the prevalence of depressive episodes in relation to latitude (20), although other researchers reported different results (21). Interestingly, a recent study found a significant inverse association between the maximum monthly increase in solar insolation and the age of onset of type I BD (22).…”

Section: Introductionmentioning

confidence: 99%

Sensitivity to Climate and Weather Changes in Euthymic Bipolar Subjects: Association With Suicide Attempts

et al. 2020

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Background: Climate and weather are known to affect multiple areas of human life, including mental health. In bipolar disorder (BD), seasonality represents an environmental trigger for mood switches, and climatic variables may contribute to recurrences. Several studies reported seasonal and climatic-related variations in the rate of suicide attempts. Suicide risk is relevant in BD, with approximately 25% of patients attempting suicide. Therefore, this study aimed to assess sensitivity to weather and climatic variations in BD subjects and its relationship with lifetime suicide attempts. Methods: Three hundred fifty-two euthymic BD and 352 healthy control subjects, homogeneous with respect to socio-demographic characteristics, were enrolled. All participants were administered the METEO-Questionnaire (METEO-Q) to evaluate susceptibility to weather and climatic changes. We also investigated the potential relationship between sensitivity to climate and weather and lifetime suicide attempts in BD patients. Results: METEO-Q scores and the number of subjects reaching the cutoff for meteorosensitivity/meteoropathy were significantly higher in BD patients. Within the clinical group, BD subjects with lifetime suicide attempts obtained higher METEO-Q scores, with no differences between BD-I and BD-II. The number of suicide attempts directly correlated with METEO-Q scores. The presence of suicide attempts was associated with the physical and psychological symptoms related to weather variations. Discussion: Our findings support the relevance of sensitivity to weather and climate variations in a large sample of BD subjects and point out the association of this feature with lifetime suicide attempts.

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“…A nationwide US material of Emergency Department admissions for suicide attempts and self-harm showed a pronounced peak from March to May [ 7 ], similar to the pattern of non-voluntary psychiatric admissions in Italy [ 8 ]. For bipolar disorder a close association exists between increase in daylight hours and both the onset of disease and subsequent hospital admissions [ 9 , 10 ]. In animals, absolute hours of daylight, but also the change in daylight hours from the previous day, affect behaviour via the retinal–hypothalamic–pineal axis [ 11 ].…”

Section: Introductionmentioning

confidence: 99%

Seasonality in trauma admissions – Are daylight and weather variables better predictors than general cyclic effects?

2018

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BackgroundTrauma is a leading global cause of death, and predicting the burden of trauma admissions is vital for good planning of trauma care. Seasonality in trauma admissions has been found in several studies. Seasonal fluctuations in daylight hours, temperature and weather affect social and cultural practices but also individual neuroendocrine rhythms that may ultimately modify behaviour and potentially predispose to trauma. The aim of the present study was to explore to what extent the observed seasonality in daily trauma admissions could be explained by changes in daylight and weather variables throughout the year.MethodsRetrospective registry study on trauma admissions in the 10-year period 2001–2010 at Oslo University Hospital, Ullevål, Norway, where the amount of daylight varies from less than 6 hours to almost 19 hours per day throughout the year. Daily number of admissions was analysed by fitting non-linear Poisson time series regression models, simultaneously adjusting for several layers of temporal patterns, including a non-linear long-term trend and both seasonal and weekly cyclic effects. Five daylight and weather variables were explored, including hours of daylight and amount of precipitation. Models were compared using Akaike’s Information Criterion (AIC).ResultsA regression model including daylight and weather variables significantly outperformed a traditional seasonality model in terms of AIC. A cyclic week effect was significant in all models.ConclusionDaylight and weather variables are better predictors of seasonality in daily trauma admissions than mere information on day-of-year.

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Solar insolation in springtime influences age of onset of bipolar I disorder

Cited by 24 publications

References 90 publications

Maximum Temperature and Solar Radiation as Predictors of Bipolar Patient Admission in an Emergency Psychiatric Ward

Maximum Temperature and Solar Radiation as Predictors of Bipolar Patient Admission in an Emergency Psychiatric Ward

Sensitivity to Climate and Weather Changes in Euthymic Bipolar Subjects: Association With Suicide Attempts

Seasonality in trauma admissions – Are daylight and weather variables better predictors than general cyclic effects?

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