Sol-gel: Uncomplicated, routine and affordable synthesis procedure for utilization of composites in drug delivery: Review

Azadani, Reyhaneh Nasr; Sabbagh, Milad; Salehi, Haniye; Cheshmi, Amir; Raza, Ali; Kumari, Beena; Erabi, Gisou

doi:10.52547/jcc.3.1.6

Cited by 20 publications

(12 citation statements)

References 151 publications

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“…There have been several articles on the salient features of these bioactive agents existing in nature which injected from nanomaterials can be used in favor of packaging applications and lesion curing [116][117][118]. However, no report has been presented on their potential usage in the face mask filter membrane using the bioactive agent.…”

Section: P R E -P R O O Fmentioning

confidence: 99%

Recent progress of filtration mechanism to fabricate the effective COVID-masks: A review

Singh

Dolatabadi

Tripathi

et al. 2021

jcc

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In the current pandemic COVID-19, which started in late 2019, humans throughout the globe are living in a situation, where all aspects of their lives either social, economic, or emotional have been affected. To inhibit the COVID-19 spread, using face masks in addition to social distancing and hand sanitation is suggested. In this survey, the idea of injecting natural agents that are biologically active into textile nanofibers is presented. Furthermore, we present recent trends which, affect the filtration efficiency of mask material. There is a wide variety of electro spinners on the market, which are easy to consume, secure, battery-powered, and handy that can be utilized to achieve the electrospun nanofiber mattresses without difficulty. The appropriate electrospun filter mats can be applied in the fully made mask. Choosing the right voltage, the right concentration, and the space in the middle of the syringe needle and the holding gatherer is of significant importance for the synthesis of uniform nanofibers.

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Section: P R E -P R O O Fmentioning

confidence: 99%

Recent progress of filtration mechanism to fabricate the effective COVID-masks: A review

Singh

Dolatabadi

Tripathi

et al. 2021

jcc

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“…Some of the approaches that have been widely used to prevent orthopedic IAI using local antibiotic release from coatings are calcium or silicon bone cements [ 13 , 14 ] and polymer hydrogels [ 7 , 8 , 15 , 16 ]. However, they have their limitations.…”

Section: Introductionmentioning

confidence: 99%

“…In addition to its biodegradability and desired antibiotic release profile, the polymer system needs to have adequate mechanical strength and matrix formation [12]. Some of the approaches that have been widely used to prevent orthopedic IAI using local antibiotic release from coatings are calcium or silicon bone cements [13,14] and polymer hydrogels [7,8,15,16]. However, they have their limitations.…”

Section: Introductionmentioning

confidence: 99%

Influence of Addition of Antibiotics on Chemical and Surface Properties of Sol-Gel Coatings

et al. 2022

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Infection is one of the most common causes that leads to joint prosthesis failure. In the present work, biodegradable sol-gel coatings were investigated as a promising controlled release of antibiotics for the local prevention of infection in joint prostheses. Accordingly, a sol-gel formulation was designed to be tested as a carrier for 8 different individually loaded antimicrobials. Sols were prepared from a mixture of MAPTMS and TMOS silanes, tris(tri-methylsilyl)phosphite, and the corresponding antimicrobial. In order to study the cross-linking and surface of the coatings, a battery of examinations (Fourier-transform infrared spectroscopy, solid-state 29Si-NMR spectroscopy, thermogravimetric analysis, SEM, EDS, AFM, and water contact angle, thickness, and roughness measurements) were conducted on the formulations loaded with Cefoxitin and Linezolid. A formulation loaded with both antibiotics was also explored. Results showed that the coatings had a microscale roughness attributed to the accumulation of antibiotics and organophosphites in the surface protrusions and that the existence of chemical bonds between antibiotics and the siloxane network was not evidenced.

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“…We know that cancer is one of the most important worldwide health issues (Azadani et al, 2021;Faraji Dizaji et al, 2020;Nouri et al, 2021). Numerous methods and drugs have been developed to fight it (Abasian et al, 2019;Asadi et al, 2019;Bazli et al, 2017;Wong Jang et al, 2020;Radmansouri et al, 2018;Rouhani et al, 2018;Sharifianjazi et al, 2020).…”

Section: Introductionmentioning

confidence: 99%

The ameliorative effects of Alpinia officinarum rhizome hydroalcoholic extract on cisplatin-induced testicular toxicity in rats

Ashtari¹,

Niazvand²,

Chamkouri³

et al. 2022

JBRA

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Objective: In this study we evaluated the influence of Alpinia officinarum rhizome extract (AO) on the alleviation of testicular damage induced by cisplatin in rats.Methods: The study groups included the control group, AO-administered group, cisplatin-administered group, and three groups administered with cisplatin and AO (different concentrations of 100, 200, and 400 mg/kg). On the 14 th day we removed the testes of the rats, and the testicular organ parameters were measured. Moreover, through the malondialdehyde concentration we assessed the oxidative stress and superoxide dismutase (SOD) activity of the testes and ran a histopathological analysis.Results: The results demonstrated that cisplatininduced oxidative stress and severe testicular damage on the AO-administered group showed no harm compared with the control group. AO-treatment in cisplatin-received rats led to the reduction of oxidative stress, enhancement of SOD activity, and prevention of testicular damage. The lowest testis damage was attributed to the group which received 400 mg/kg of AO compared to 100 and 200 mg/ kg.Conclusions: Overall, the Cis+/AO+400 group had the best antioxidant effect. The findings could lead to changes in cancer care guidelines that incorporate phytochemicals, making cancer therapies safer.

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Sol-gel: Uncomplicated, routine and affordable synthesis procedure for utilization of composites in drug delivery: Review

Cited by 20 publications

References 151 publications

Recent progress of filtration mechanism to fabricate the effective COVID-masks: A review

Recent progress of filtration mechanism to fabricate the effective COVID-masks: A review

Influence of Addition of Antibiotics on Chemical and Surface Properties of Sol-Gel Coatings

The ameliorative effects of Alpinia officinarum rhizome hydroalcoholic extract on cisplatin-induced testicular toxicity in rats

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