Sol–gel silica-based biomaterials and bone tissue regeneration

Structure and Characterization of Some High Chemically Resistance Silicate Glasses

“…The maximum pH values were recorded in all the samples after 14 days immersion compared with the initial pH of the SBF solution (pH = 7.4). The pH values on fourteen days were measured as pH = 7.71, 7.75, 7.78, and 7.89 for the glass samples G 1 , G 3 , G 5 [40]. The results also showed that the base glass composition i.e.…”

“…The limitation associated with Si-based bioactive glasses is the slow rate of degradation and conversion to apatite which further complicates the rate of implant resorption and simultaneous bone growth [4]. When the SiO 2 content exceeds 60 %, the bioactive glass is not able to induce the formation of apatite layer even after several weeks immersion in SBF solution and it failure to bond to either bone or soft tissue [5]. The main reason is that high SiO 2 -containnng glasses prepared by the melt derived method lead to increase the rigidity of the glass structure and do not easily liberate alkali or alkaline cations, leading to insufficient silanol groups on the surface of glasses to motivate the apatite layer formation.…”

Effect of textural properties on the drug delivery behaviour of nanoporous TiO2 matrices

“…These studies deal with either polymeric materials and/or with inorganic oxides, such as nanoporous alumina, porous silicon, nanostructured ceramics and nanostructured TiO2 [1][2][3]. Among these systems titanium and TiO2 materials are well known in the biomedical applications since the 1970s for their use as orthopaedic implants.…”

Effect of alkali earth oxides on hydroxy-carbonated apatite nano layer formation for SiO2–BaO–CaO–Na2O–P2O5 glass system

“…Sol-gel glasses can be produced at low temperature conditions with good homogeneity. The sol-gel method offers potential benefits for obtaining the powdered materials with good control of composition, microstructure, and wider range of bioactivity (Ahmed et al 2012;Bellucci et al 2012;Goller et al 2004;Arcos and Vallet-Regíl 2010). Sol-gel process is a more convenient technique than melt quenching technique to improve HCA layer growth rate in simulated body fluid (SBF) solution based on dissolution property of synthesised glass-ceramics in SBF solution.…”