Software framework for spatially tracked pre-beamformed RF data with a freehand clinical ultrasound transducer

Kang, Hyun Jae; Guo, Xiangming; Azar, Reza Zahiri; Cheng, Alexis; Boctor, Emad M.

doi:10.1117/12.2044226

Cited by 2 publications

(3 citation statements)

References 13 publications

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“…Prebeamformed photoacoustic images were displayed in real time at a rate of 3 to 5 frames per second to assist with seed localization. The software framework for real-time photoacoustic imaging with this system was described in a previous publication, 38 while the commercial SonixTouch US system and software were utilized to acquire linear and curvilinear US images (i.e., images acquired with the linear and curvilinear arrays, respectively). The sampling rate for data acquisition was 40 MHz, and the bandwidths of the linear and curvilinear arrays were 4 to 8 MHz and 5 to 9 MHz, respectively.…”

Section: Phantom Experimentsmentioning

confidence: 99%

Transurethral light delivery for prostate photoacoustic imaging

et al. 2015

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Abstract. Photoacoustic imaging has broad clinical potential to enhance prostate cancer detection and treatment, yet it is challenged by the lack of minimally invasive, deeply penetrating light delivery methods that provide sufficient visualization of targets (e.g., tumors, contrast agents, brachytherapy seeds). We constructed a sidefiring fiber prototype for transurethral photoacoustic imaging of prostates with a dual-array (linear and curvilinear) transrectal ultrasound probe. A method to calculate the surface area and, thereby, estimate the laser fluence at this fiber tip was derived, validated, applied to various design parameters, and used as an input to three-dimensional Monte Carlo simulations. Brachytherapy seeds implanted in phantom, ex vivo, and in vivo canine prostates at radial distances of 5 to 30 mm from the urethra were imaged with the fiber prototype transmitting 1064 nm wavelength light with 2 to 8 mJ pulse energy. Prebeamformed images were displayed in real time at a rate of 3 to 5 frames per second to guide fiber placement and beamformed offline. A conventional delay-and-sum beamformer provided decreasing seed contrast (23 to 9 dB) with increasing urethra-to-target distance, while the shortlag spatial coherence beamformer provided improved and relatively constant seed contrast (28 to 32 dB) regardless of distance, thus improving multitarget visualization in single and combined curvilinear images acquired with the fiber rotating and the probe fixed. The proposed light delivery and beamforming methods promise to improve key prostate cancer detection and treatment strategies.

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Section: Phantom Experimentsmentioning

confidence: 99%

Transurethral light delivery for prostate photoacoustic imaging

et al. 2015

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“…A layer of ultrasound transmission gel was placed between the phantom and hand-held US probe, which was rotated about its elevation axis with minimal rotations about the axial and lateral axes. Transistor-transistor logic (TTL) trigger signals from the laser system were converted to a RS232 protocol with our custom-built controller board, and sent to our MUSiiC toolkit software, which contains a MUSiiC-DAQServer [44] to acquire channel data frames in real-time and measure the data acquisition timestamp of each PA frame, a spatial tracking software module ( MUSiiC-TrackerServer [44]) to acquire EM tracking information, a MUSiiC-Sync software module to synchronize simultaneously acquired 2D PA frame and pose information, and a MUSiiC-Stream Writer software module to save spatially-tracked 2D frames to a local hard disk. Spatial-angular compounding methods were then applied off-line.…”

Section: Methodsmentioning

confidence: 99%

“…To implement the technique, an external spatial tracking device such as an electromagnetic (EM) position sensor is used to simultaneously record the spatial position and orientation (i.e. pose) information of the ultrasound probe and acquire PA images [44]. This pose information is used to filter images in similar planes, and the filtered images are combined with user-defined thresholds to form a single compounded PA image.…”

Section: Introductionmentioning

confidence: 99%

Spatial Angular Compounding ofPhotoacoustic Images

Kang

Bell

Guo

et al. 2016

IEEE Trans. Med. Imaging

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Photoacoustic (PA) images utilize pulsed lasers and ultrasound transducers to visualize targets with higher optical absorption than the surrounding medium. However, they are susceptible to acoustic clutter and background noise artifacts that obfuscate biomedical structures of interest. We investigated three spatial-angular compounding methods to improve PA image quality for biomedical applications, implemented by combining multiple images acquired as an ultrasound probe was rotated about the elevational axis with the laser beam and target fixed. Compounding with conventional averaging was based on the pose information of each PA image, while compounding with weighted and selective averaging utilized both the pose and image content information. Weighted-average compounding enhanced PA images with the least distortion of signal size, particularly when there were large (i.e. 2.5 mm and 7°) perturbations from the initial probe position. Selective-average compounding offered the best improvement in image quality with up 181, 1665, and 1568 times higher contrast, CNR, and SNR, respectively, compared to the mean values of individual PA images. The three presented spatial compounding methods have promising potential to enhance image quality in multiple photoacoustic applications.

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Software framework for spatially tracked pre-beamformed RF data with a freehand clinical ultrasound transducer

Cited by 2 publications

References 13 publications

Transurethral light delivery for prostate photoacoustic imaging

Transurethral light delivery for prostate photoacoustic imaging

Spatial Angular Compounding ofPhotoacoustic Images

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