Soft Tissue Tumors

Clinicopathologic Prognostic Factors of Pure Myxoid Liposarcoma of the Extremities and Trunk Wall

“…The tumor is low grade according to one report [7]. However, when they do metastasize, in contrast to other liposarcoma variants they tend to metastasize to unusual locations with worse prognosis [3,8,22].…”

“…Myxoid liposarcoma is the second most common type of liposarcoma, representing approximately one-third of all liposarcomas [7] and 6% of all adult soft tissues sarcomas. The tumor is low grade according to one report [7].…”

Molecular cytogenetics of bone and soft tissue tumors

“…The term "soft tissue tu m o r" is used to denote a subgroup of these neoplasm s a n d includes synovial sarcom as, fibrosar comas, liposarcom as, leiom yosarcom as, rhabdom yosarco mas, angiosarcom as, an d the m ost com m on form , m alignant fibrous histiocytom as [1]. Cytogenetic studies have revealed the occurrence of b o th num erical an d stru c tu ral abnorm alities in several of these tum ors, in clu d in g recurrent chrom osom al trans locations [2][3][4][5].…”

“…Synovial sarcom a is a soft tissue tumor that predom i n an tly afflicts adolescents and young adults [1]. Despite their designation, it is n o w generally accepted that these tum ors m ay n o t originate from synovial tissue but, instead, from m u ltip o ten t stem cells that are capable of differentiat ing into m esen ch y m al an d /o r epithelial structures [1,13].…”

“…Despite their designation, it is n o w generally accepted that these tum ors m ay n o t originate from synovial tissue but, instead, from m u ltip o ten t stem cells that are capable of differentiat ing into m esen ch y m al an d /o r epithelial structures [1,13]. F urtherm ore, in spite of its predom inant occurrence in the low er a n d u p p e r extrem ities, synovial sarcomas m ay also be fo u n d in several other body locations such as head, neck, and trunk.…”