Soft Tissue Sarcomas of the Chest Wall

Tsukushi, Satoshi; Nishida, Yoshihiro; Sugiura, Hideshi; Nakashima, Hiroatsu; Ishiguro, Naoki

doi:10.1097/jto.0b013e3181a97da3

Cited by 51 publications

(48 citation statements)

References 11 publications

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“…The data about treatment outcome and prognostic factors for patients with primary STS of thoracic wall is limited while it is usually evaluated together with extremity or retroperitoneal sarcomas (Berna et al, 2012;Roger et al, 2013). Besides, in many studies patients with rhabdomyosarcoma, bone and cartilagious chest wall tumors, borderline tumors like desmoids tumors, dermatofibrosarcoma protuberans and patients with tumors metastatic to the chest wall were included in the analysis (Pairolero et al, 1985;Coindre et al, 2001;Athanassiadi et al, 2001;Warzelhan et al, 2001;Salas et al, 2009;Tsukushi et al, 2009;Van Geel et al, 2011). Few studies focused exclusively on soft tissue tumors originally from chest wall alone are available (Greager et al, 1987;Gordon et al, 1991;Gross et al, 2005).…”

Section: Discussionmentioning

confidence: 99%

“…Thoracic wall STS were usually evaluated together with STS of other primary sites or bone and cartilaginous chest wall tumors due to their rarity (Pairolero et al, 1985;Athanassiadi et al, 2001;Coindre et al, 2001;Warzelhan., Gross et al, 2005;Salas et al, 2009;Tsukushi et al, 2009;Jamal et al, 2010;Shah et al, 2010;Van Geel et al, 2011;Berna et al, 2012;Roger et al, 2013). While there are limited data about the prognostic factors for the patients with primary thoracic wall STS, they are generally treated like extremity sarcomas since the prognostic factors and the clinical behavior of thoracic wall sarcomas assumed to be similar to extremity STS (Greager et al, 1987;Gordon et al, 1991;Gross et al, 2005).…”

Section: Introductionmentioning

confidence: 99%

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Long-Term Treatment Results in Soft Tissue Sarcomas of the Thoracic Wall Treated with Pre-or-Postoperative Radiotherapy - a Single Institution Experience

Öksüz¹,

Özdemir²,

Kaydıhan³

et al. 2014

Asian Pacific Journal of Cancer Prevention

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Objective: To evaluate the long term results among patients with soft tissue sarcoma of the thoracic wall. Materials and Methods: Twenty-six patients who were treated with pre-or postoperative radiotherapy between December 1980-December 2007, with a diagnosis of soft tissue sarcoma of the thoracic wall were retrospectively evaluated. Results: The median age was 44 years (14-85 years) and 15 of them were male. A total of 50% of patients were grade 3. The most common histologic type of tumor was undifferentiated pleomorphic sarcoma (26.9%). Tumor size varied between 2-25 cm (median 6.5 cm). Seventeen of the cases had marginal and 9 had wide local resection. Four cases received preoperative radiotherapy and 22 postoperative radiotherapy. Six of the patients with large and high grade tumors received chemotherapy. Median follow-up time was 82 months (9-309 months). Local recurrence and metastasis was detected in 34.6% and 42.3% of patients, respectively. Fiveyear local control (LC), disease-free survival (DFS), overall survival (OS), and disease-specific survival (DSS) were 62%, 38%, 69%, and 76% respectively. On univariate analysis, the patients with positive surgical margins had a markedly lower 5-year LC rate than patients with negative surgical margin, but the difference was not significant (43% vs 78%, p=0.1). Five-year DFS (66% vs 17%) and DSS (92% vs 60%) rates were significantly worse for the patients who had high grade tumors (p=0.01, p=0.008 respectively). Conclusions: Tumor grade and surgical margin are essential parameters for determining the prognosis of thoracic wall soft tissue sarcoma both in our series and the literature.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Long-Term Treatment Results in Soft Tissue Sarcomas of the Thoracic Wall Treated with Pre-or-Postoperative Radiotherapy - a Single Institution Experience

Öksüz¹,

Özdemir²,

Kaydıhan³

et al. 2014

Asian Pacific Journal of Cancer Prevention

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“…Our cohort included 3 groups: (I) bony sarcomas as osteosarcomas, chondrosarcomas, and primitive neuroectodermal tumor (PNET)/Ewing's sarcoma; (II) soft tissue sarcoma as fibromatosis/fibrosarcoma, pleomorphic undifferentiated sarcoma previously named malignant fibrous histiocytoma, dermatofibrosarcoma protuberans, synovial sarcoma, angiosarcoma, myxofibrosarcoma, rhabdomyosarcoma , myxoliposarcoma; (III) others as carcinomas, solitary plasma cell myeloma and lymphoma that were initially diagnosed as liposarcoma (9)(10)(11)(12).…”

Section: Patients and Data Collectionmentioning

confidence: 99%

Contributing factors to the outcome of primary malignant chest wall tumors

et al. 2017

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Background: Primary malignant chest-wall tumors (PMCWTs) are a heterogeneous group of tumors.They require a special experience in designing resection and reconstruction. They account for less than 1% of all primary malignant tumors. This study is designed to clarify different factors contributing to the outcome of patients with PMCWTs in our institution. Methods: A retrospective study included 98 patients with pathology proven PMCWTs, treated at the National Cancer Institute (NCI), Cairo University, Egypt, during the past 10 years.

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“…In recurrent cases, even if infiltration of skeletal tissue does not occur, resection of chest wall should be performed to ensure disease-free surgical margin. [9] For high-grade tumors, adequate surgical margin is 4 cm in width, while for low-grade tumors, surgical margins of 1-2 cm in width will usually suffice. [7] Therefore, for satisfactory surgery, full-thickness chest wall resection should be performed in cases with chest wall sarcoma.…”

Section: Discussionmentioning

confidence: 99%

Multidisciplinary Approach and Clinical Algorithm in Resection and Reconstruction for Chest Wall Tumor

Demirhan¹

2017

South Clin Ist Euras

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Objective: The aim of this study was to retrospectively review files of patients who had tumor resection and reconstructive surgery performed by thoracic and plastic surgeons due to chest wall tumor, and to create reconstruction algorithm. Methods:Records of 45 patients who underwent surgery for chest wall tumor between 2006-2014 were included in this study. Data including age, sex, tumor localization, defect size, quantity of resected costa and bone, and method of skeletal and soft tissue reconstruction were gathered retrospectively from patient files. Results:The largest defect was 325 cm 2 and smallest was 36 cm 2 . Titanium mesh was used in 54% of patients, while prolene mesh was used in 32%. Pectoralis kite flap (n=14), latissumus dorsi muscle-skin muscle flap (n=12), latissumus dorsi muscle flap and pectoral kite flap (n=5), vertical rectus abdominus skin muscle flap (n=6), omentum flap (n=3), transvers rectus abdominus skin muscle flap (n=3), free anterolateral thigh flap (n=2), and local rotation flap (n=1) were used for soft tissue reconstruction. Conclusion:Algorithm for soft and skeletal tissue reconstruction was created in accordance with obtained data.

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Soft Tissue Sarcomas of the Chest Wall

Cited by 51 publications

References 11 publications

Long-Term Treatment Results in Soft Tissue Sarcomas of the Thoracic Wall Treated with Pre-or-Postoperative Radiotherapy - a Single Institution Experience

Long-Term Treatment Results in Soft Tissue Sarcomas of the Thoracic Wall Treated with Pre-or-Postoperative Radiotherapy - a Single Institution Experience

Contributing factors to the outcome of primary malignant chest wall tumors

Multidisciplinary Approach and Clinical Algorithm in Resection and Reconstruction for Chest Wall Tumor

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