Soft tissue myoepithelial carcinoma of neck: A rare case report with review of literature

Swain, Niharika; Kumar, Shria; Pathak, Jigna; Patel, Shilpa

doi:10.1016/j.ajoms.2013.07.014

Cited by 5 publications

(5 citation statements)

References 13 publications

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“…Sometimes they may show central necrosis, but they generally lack calcifications, fat and bone involvement. 5,6 The present case displayed a peculiar radiological pattern, characterized by a prevailingly cystic appearance. The main differential diagnoses of childhood cystic or mixed solid-cystic lesions of the lateral neck include necrotic/infected lymph nodes or abscesses, branchial cleft cysts, vascular malformations, and neoplasms such as teratomas and vascular tumors.…”

Section: Discussionmentioning

confidence: 60%

Congenital Myoepithelial Carcinoma of Soft Tissue Associated With Cystic Myoepithelioma

et al. 2017

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Myoepithelial neoplasms of soft tissue represent a heterogeneous group of lesions, encompassing both benign entities as myoepithelioma (ME) and highly aggressive tumors as myoepithelial carcinoma (MEC). We describe a case of pediatric soft tissue MEC with peculiar features that may lead to misdiagnosis: congenital onset and presence of a benign component with predominant cystic structure. Few cases of congenital MEC have been reported, but the coexistence of MEC with ME is even more rare, accounting for less than 1% of myoepithelial tumors. Moreover, an extensive cystic appearance had never been described in either ME or MEC of soft tissue. Despite several predictors of poor prognosis, the patient has been showing a favorable clinical course since the administration of ICpE (ifosfamide, cisplatin, and etoposide) chemotherapy. This report provides valuable information in the differential diagnosis of cystic congenital tumors and supports a possible efficacy of adjuvant combined treatment for patients with localized disease after surgery.

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Section: Discussionmentioning

confidence: 60%

Congenital Myoepithelial Carcinoma of Soft Tissue Associated With Cystic Myoepithelioma

et al. 2017

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“…Extensive research and literature review are necessary to explore therapeutic and prognostic targets in the context of personalized medicine. Given the limited number of Indian case reports on this entity, further studies are needed to expand our understanding of this rare condition in the Indian population [9][10][11].…”

Section: Discussionmentioning

confidence: 99%

Primary cutaneous myoepithelial carcinoma A report of two cases with literature review

Mullappli P

2023

JCIMCR

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“…We did not include any lesions that involved both dermal and soft tissue, as these are better classified as cutaneous lesions. With these criteria, we identified a total of 58 cases of soft tissue myoepithelial carcinoma (Table ) …”

Section: Discussionmentioning

confidence: 99%

“…With these criteria, we identified a total of 58 cases of soft tissue myoepithelial carcinoma (Table 1). 5,7,[11][12][13][14][15][16][17][18][19][20][21][22][23][24][25][26][27][28][29][30]…”

Section: Discussionmentioning

confidence: 99%

Neoadjuvant radiation therapy for the management of myoepithelial carcinoma of the upper extremity

Kabarriti

Quinn

Ewart

et al. 2017

Intl Journal of Cancer

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Myoepithelial tumors of the soft tissue are a rare tumor displaying myoepithelial elements and lacking obvious ductal differentiation. The rarity of these precludes any evidence-based consensus regarding optimal management. Nevertheless, the current approach to these lesions begins with amputation or complete excision. The efficacy of neoadjuvant or adjuvant radiation therapy or chemotherapy has not been established. Here, we present the first report to the authors’ knowledge of neoadjuvant radiation therapy for the treatment of this rare soft tissue neoplasm and review the management and outcomes of published cases of myoepithelial carcinoma. A patient with a soft tissue myoepithelial carcinoma that declined both amputation and chemotherapy was treated with neoadjuvant radiation therapy and wide surgical excision followed by a brachytherapy boost to the resected tumor bed. Neoadjuvant radiation therapy resulted in an excellent response with extensive treatment-related changes consisting predominantly of fibrosis, hyalinization and hemorrhage and only 10% residual viable myoepithelial carcinoma present in the surgical specimen.

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Soft tissue myoepithelial carcinoma of neck: A rare case report with review of literature

Cited by 5 publications

References 13 publications

Congenital Myoepithelial Carcinoma of Soft Tissue Associated With Cystic Myoepithelioma

Congenital Myoepithelial Carcinoma of Soft Tissue Associated With Cystic Myoepithelioma

Primary cutaneous myoepithelial carcinoma A report of two cases with literature review

Neoadjuvant radiation therapy for the management of myoepithelial carcinoma of the upper extremity

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