Soft-tissue masses: histologic basis for decreased signal (short T2) on T2-weighted MR images

Sundaram, Murali; Mh, McGuire; Schajowicz, Fritz

doi:10.2214/ajr.148.6.1247

Cited by 242 publications

(122 citation statements)

References 4 publications

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“…These findings were similar and consistent with previous reports (10,11,18). Recently, several MRI features of desmoid tumors have been reported and some researchers have correlated the various signal intensities of the mass on the T2-weighted images with histopathologic findings such as cellular, collagen, and myxoid components through the excellent soft tissue contrast resolution of MRI (6,14,19). Consistent with previous reports (20), most of the desmoid tumors in our study also showed T2 low signal intensity band-like lesions (so called band sign) that corresponded with pathologically dense collagenous stroma.…”

Section: Discussionsupporting

confidence: 91%

The Imaging Features of Desmoid Tumors: the Usefulness of Diffusion Weighted Imaging to Differentiate between Desmoid and Malignant Soft Tissue Tumors

Lee

Choi

et al. 2017

Investig Magn Reson Imaging

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Section: Discussionsupporting

confidence: 91%

The Imaging Features of Desmoid Tumors: the Usefulness of Diffusion Weighted Imaging to Differentiate between Desmoid and Malignant Soft Tissue Tumors

Lee

Choi

et al. 2017

Investig Magn Reson Imaging

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“…This appearance is typical (although not diagnostic) of densely collagenous, hypocellular lesions [2] and is different from that of the usual renal malignancy; it should alert one to the possibility that a benign medullary fibroma is present.…”

Section: Mr Imaging Findings In Renal Medullary Fibromamentioning

confidence: 85%

MR imaging findings in renal medullary fibroma

Cormier

Patel

Turner

et al. 1989

American Journal of Roentgenology

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“…MR imaging offers the advantages of excellent soft-tissue contrast and lack of exposure to ionizing radiation. For various reasons, softtissue masses usually demonstrate high signal intensity on T2-weighted MR images, and several previous studies have reported malignant lymph nodes to have higher signal intensity than benign lymph nodes on T2-or contrast-enhanced T1-weighted MR images (24)(25)(26). Evaluation of signal intensity and morphologic features such as internal necrosis was feasible on the MR images of PET/MR scans.…”

Section: Discussionmentioning

confidence: 99%

Clinical Implication of PET/MR Imaging in Preoperative Esophageal Cancer Staging: Comparison with PET/CT, Endoscopic Ultrasonography, and CT

et al. 2014

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This was a study to compare the diagnostic efficacies of endoscopic ultrasonography (EUS), CT, PET/MR imaging, and PET/CT for the preoperative local and regional staging of esophageal cancer, with postoperative pathologic stage used as the reference standard. Methods: During 1 y, 19 patients with resectable esophageal cancer were enrolled and underwent preoperative EUS, CT, PET/CT, and PET/MR imaging. A chest radiologist and nuclear medicine physician retrospectively reviewed the images and assigned tumor and lymph node stages according to the seventh version of the TNM system and the American Joint Committee on Cancer staging system. Four patients who were treated nonsurgically were excluded from data analysis. The efficacies of EUS, CT, PET/CT, and PET/MR imaging were compared. Results: Primary tumors were correctly staged in 13 (86.7%), 10 (66.7%), and 5 (33.3%) patients at EUS, PET/MR imaging, and CT, respectively (P value ranging from 0.021 to 0.375). The accuracy of determining T1 lesions was 86.7%, 80.0%, and 46.7% for EUS, PET/MR imaging, and CT, respectively. For distinguishing T3 lesions, the accuracy was 93.3% for EUS and 86.7% for both PET/MR imaging and CT. For lymph node staging, the accuracy was 83.3%, 75.0%, 66.7%, and 50.0% for PET/MR imaging, EUS, PET/CT, and CT, respectively. In addition, area-under-the-curve values were 0.800, 0.700, 0.629, and 0.543 for PET/MR imaging, EUS, PET/CT, and CT, respectively. Conclusion: PET/MR imaging demonstrated acceptable accuracy for T staging compared with EUS and, although not statistically significant, even higher accuracy than EUS and PET/CT for prediction of N staging. With adjustments in protocols, PET/MR imaging may provide an important role in preoperative esophageal cancer staging in the future. Accur ate staging of esophageal cancer is critical for decisions on patient treatment. Current practice guidelines for the staging of esophageal cancer include CT of the chest and abdomen, endoscopic ultrasonography (EUS), and PET/CT (1). EUS is a relatively accurate modality for evaluating primary tumor depth compared with CT, which cannot identify the histologic layers of the esophageal wall; thus, the role of CT is usually limited to exclusion of T4 cancers (2,3).Considering nodal metastasis, CT scans, which depend on size criteria, have relatively poor diagnostic performance, as enlarged lymph nodes may be reactive and normal-sized lymph nodes may be positive for metastasis (4,5). Currently, a combination of EUS with or without fine-needle aspiration and PET/CT is widely accepted for assessment of nodal metastasis (1). However, certain lymph nodes that are not immediately adjacent to the esophagus could be dismissed, and the EUS probes, which are typically larger than standard endoscopic probes, are not feasible if the lumen has been narrowed by a large tumor or stricture. PET/CT supports the role of EUS and CT because the maximum standardized uptake value helps identify patients with T1 cancers and pathologic lymph nodes, but the diagnostic accuracy stil...

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Soft-tissue masses: histologic basis for decreased signal (short T2) on T2-weighted MR images

Cited by 242 publications

References 4 publications

The Imaging Features of Desmoid Tumors: the Usefulness of Diffusion Weighted Imaging to Differentiate between Desmoid and Malignant Soft Tissue Tumors

The Imaging Features of Desmoid Tumors: the Usefulness of Diffusion Weighted Imaging to Differentiate between Desmoid and Malignant Soft Tissue Tumors

MR imaging findings in renal medullary fibroma

Clinical Implication of PET/MR Imaging in Preoperative Esophageal Cancer Staging: Comparison with PET/CT, Endoscopic Ultrasonography, and CT

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