Soft Lens Design, Fitting, and Physiologic Response

Little, Simon A.

doi:10.1016/b978-0-7506-7517-8.50019-5

Cited by 1 publication

(2 citation statements)

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“…While FL, RB and LG are not molecular probes, they are excellent tools for highlighting gross structural changes in pathological conditions. There are six types of clinically important corneal staining in contact lens wearers: mechanical, exposure, metabolic, toxic, inflammatory and infectious (Table ) . These pathological conditions in contact lens wearers where corneal staining may occur can be differentiated from: each other pathological situations in non‐contact lens wearers that may mimic those found in contact lens wearers and hyperfluorescence in non‐pathological situations (Tables and ) .…”

Section: Corneal and Conjunctival Stainingmentioning

confidence: 99%

“…In situations of corneal abrasion, the pattern often provides the necessary clues to indicate the aetiology of the staining (Table ) . These conditions tend to be unilateral and are accompanied by mild‐to‐moderate signs and symptoms, although in the case of superior epithelial arcuate lesions (SEALs), patients may be asymptomatic without any additional signs.…”

Section: Corneal and Conjunctival Stainingmentioning

confidence: 99%

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Putting vital stains in context

Efron

2013

Clinical and Experimental Optometry

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While vital staining remains a cornerstone in the diagnosis of ocular disease and contact lens complications, there are many misconceptions regarding the properties of commonly used dyes by eye‐care practitioners and what is and what is not corneal staining after instillation of sodium fluorescein. Similarly, the proper use and diagnostic utility of rose Bengal and lissamine green B, the other two ophthalmic dyes commonly used for assessing ocular complications, have similarly remained unclear. Due to the limitations of vital stains for definitive diagnosis, concomitant signs and symptoms in addition to a complete patient history are required. Over the past decade, there have been many reports of a type of corneal staining—often referred to as solution‐induced corneal staining (SICS)—that is observed with the use of multipurpose solutions in combination with soft lenses, more specifically silicone hydrogel lenses. Some authors believe that SICS is a sign of lens/solution incompatibility; however, new research shows that SICS may be neither a measure of lens/solution biocompatibility nor ‘true’ corneal staining, as that observed in pathological situations. A large component of SICS may be a benign phenomenon, known as preservative‐associated transient hyperfluorescence (PATH). There is a lack of correlated signs and/or symptoms with SICS/PATH. Several properties of SICS/PATH, such as appearance and duration, differentiate it from pathological corneal staining. This paper reviews the properties of vital stains, their use and limitations in assessment of the ocular surface, the aetiology of corneal staining, characteristics of SICS/PATH that differentiate it from pathological corneal staining and what the SICS/PATH phenomenon means for contact lens‐wearing patients.

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