Sodium Metaperiodate Oxidation of Isocarvacrol

Abstract

Sodium metaperiodate oxidation of isocarvacrol 8, a monoterpene phenol has been found to give hydrothymoquinone 13, a natural product and a ring cleavage product 7-oxo-5-isopropyloct-3-en-2,5-olide 14.

A Convenient One-Pot Synthesis of 4-Methyl-3-Phenyl-, 3-Aryl- and 3-Aryl-4-Phenylcoumarins

“…Our interest in thermal reactions [6][7][8] prompted us to develop a simple and general procedure for the synthesis of 4-methyl-3-phenylcoumarins 3a-e, 3-arylcoumarins 3f-m and 3-aryl-4-phenylcoumarins 3n-p in yield ranging from 41 to 89%. Our interest in thermal reactions [6][7][8] prompted us to develop a simple and general procedure for the synthesis of 4-methyl-3-phenylcoumarins 3a-e, 3-arylcoumarins 3f-m and 3-aryl-4-phenylcoumarins 3n-p in yield ranging from 41 to 89%.…”