Sodium lauryl sulfate and its potential impacts on organisms and the environment: A thematic analysis

Asio, Johannes Reiner G.; Garcia, Janice S.; Antonatos, Charalabos; Sevilla-Nastor, Janice B.; Trinidad, Lorele C.

doi:10.1016/j.emcon.2023.100205

Cited by 12 publications

(14 citation statements)

References 20 publications

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“…(52) This surfactant is rarely monitored and remains unregulated due to its biodegradable nature, but its risks have been debated. (53) Longitudinal Stability of the Chemical Exposome. The final combined dataset of 519 annotated substances (Level 1 and 2) was used to examine the intra-and inter-individual variation of exposure in this 2-year study with six sampling points.…”

Section: Resultsmentioning

confidence: 99%

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Longitudinal Exposomics in a Multiomic Wellness Cohort Reveals Distinctive and Dynamic Environmental Chemical Mixtures in Blood

Sdougkou,

Papazian,

Bonnefille

et al. 2024

Preprint

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Chemical exposomes can now be comprehensively measured in human blood, but robust application of chemical exposomics in cohort studies requires knowledge of the longitudinal stability and interindividual variability of exogenous molecular profiles. Here we applied chemical exposomics to plasma of 46 adults, each sampled six times over two years in a multiomic wellness cohort. New chemicals were discovered, distinctive co-exposure patterns were observed, and intra-class correlation coefficients (ICC) for 519 confidently annotated substances are reported to support study design. Longitudinal stability of the chemical exposome (mean ICC 0.30) was significantly lower than the proteome, metabolome, lipidome or microbiome, and must be measured more frequently than other molecular profiles in health studies. Mixed-effects models nevertheless revealed significant associations between testosterone and perfluoroalkyl substances, and significant time-trends for low and high stability exposures alike. Complex exposome data structures were visualized and explored, demonstrating great potential for longitudinal exposomics in precision health research.

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Section: Resultsmentioning

confidence: 99%

“…(52) This surfactant is rarely monitored and remains unregulated due to its biodegradable nature, but its risks have been debated. (53)…”

Section: Resultsmentioning

confidence: 99%

Longitudinal Exposomics in a Multiomic Wellness Cohort Reveals Distinctive and Dynamic Environmental Chemical Mixtures in Blood

Sdougkou,

Papazian,

Bonnefille

et al. 2024

Preprint

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“…We expect this approach also to be important for other detergent classes. For example, anionic surfactants contribute to 60 % of world surfactant production, thus leading to a constant flux of these compounds into ecosystems [57] . However, their level of toxicity and behaviour in environmental compartments has not yet been fully understood.…”

Section: Resultsmentioning

confidence: 99%

Trends in the Diversification of the Detergentome

Wycisk,

Wagner,

Urner

2023

ChemPlusChem

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Detergents are amphiphilic molecules that serve as enabling steps for today’s world applications. The increasing diversity of the detergentome is key to applications enabled by detergent science. Regardless of the application, the optimal design of detergents is determined empirically, which leads to failed preparations, and raising costs. To facilitate project planning, here we review synthesis strategies that drive the diversification of the detergentome. Synthesis strategies relevant for industrial and academic applications include linear, modular, combinatorial, bio‐based, and metric‐assisted detergent synthesis. Scopes and limitations of individual synthesis strategies in context with industrial product development and academic research are discussed. Furthermore, when designing detergents, the selection of molecular building blocks, i.e., head, linker, tail, is as important as the employed synthesis strategy. To facilitate the design of safe‐to‐use and tailor‐made detergents, we provide an overview of established head, linker, and tail groups and highlight selected scopes and limitations for applications. It becomes apparent that most recent contributions to the increasing chemical diversity of detergent building blocks originate from the development of detergents for membrane protein studies. The overview of synthesis strategies and molecular blocks will bring us closer to the ability to predictably design and synthesize optimal detergents for challenging future applications.

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“…However, commercial soaps containing sodium lauryl sulfate (SLS) are frequently associated with skin dryness and irritation [7], prompting a shift towards organic soaps. These soaps exclude harmful SLS chemicals in favor of alternative bio-surfactants, offering a safer option for body care and mitigating environmental impact [8][9][10].…”

Section: Introductionmentioning

confidence: 99%

Comparison of Organic Liquid Soap Made from Papaya-Turmeric and Aloe Vera-Piper Betel

Juninho,

Syamsudin,

Handayani

et al. 2024

JKPK

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<p>In the wake of the COVID-19 pandemic, the imperative to mitigate pathogen transmission has catalyzed the innovation of soaps imbued with antimicrobial and antibacterial properties. Diverging from conventional reliance on synthetic chemicals, often associated with adverse dermatological reactions, this study explores the formulation of organic liquid soaps. These soaps leverage naturally occurring antibacterial and antimicrobial compounds from readily accessible plants, presenting a viable alternative to commercially available inorganic body washes predominantly manufactured by small to medium-sized enterprises. Specifically, this research harnesses papaya and aloe vera extracts for their antimicrobial attributes, augmented with turmeric and piper betel for enhanced antibacterial efficacy. Despite the recognized potency of turmeric and piper betel, variability in their effectiveness necessitates rigorous validation against the Indonesian National Standards (SNI) to ensure product quality and safety. This includes comprehensive evaluations of pH levels, density, Total Plate Count (TPC), and Mold and Yeast Count (MYC) to certify the soap's inhibitory capacity against bacterial and fungal proliferation. Employing maceration and hot processing techniques, the formulated papaya-based soap adhered to SNI 4085:2017 criteria for pH and MYC, although initially failing the TPC test. Subsequent incorporation of turmeric extract facilitated compliance with all SNI benchmarks. Conversely, aloe vera formulations only satisfied pH requirements under the SNI, even after adding piper betel. However, substituting piper betel with turmeric extract enabled the aloe vera soap to fulfill the requisite SNI parameters. These findings underscore turmeric extract's superior antibacterial properties, positioning it as a pivotal component in papaya and aloe vera soap formulations. Contrary to prevalent assumptions regarding piper betel's antimicrobial and antibacterial effectiveness, our investigation substantiates turmeric's superior role in bacterial growth inhibition within organic soap matrices.</p>

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Sodium lauryl sulfate and its potential impacts on organisms and the environment: A thematic analysis

Cited by 12 publications

References 20 publications

Longitudinal Exposomics in a Multiomic Wellness Cohort Reveals Distinctive and Dynamic Environmental Chemical Mixtures in Blood

Longitudinal Exposomics in a Multiomic Wellness Cohort Reveals Distinctive and Dynamic Environmental Chemical Mixtures in Blood

Trends in the Diversification of the Detergentome

Comparison of Organic Liquid Soap Made from Papaya-Turmeric and Aloe Vera-Piper Betel

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