“…Traditionally, several modalities such as using local and/or systemic steroids, removing vitreous scaffolds, using localized radiation, repositioning of uveal tissue, and performing meticulous wound closure have been suggested to overcome this devastating complication. [4][5][6][7] More recently, proactive treatment approach (which involves limited vitrectomy during the primary repair, heavy topical corticosteroid therapy, and complete vitrectomy on Day 3) 8 and neutralizing the undesirable intraocular mechanical forces generated by PVR via preventive scleral buckling have also shown encouraging results. 9,10 However, there is still a need for finding more safe and effective alternatives.…”