Sodium‐glucose transport protein 2 inhibitor use in the management of insulin dysregulation in ponies and horses
Nicola J. Menzies‐Gow,
Edward J. Knowles
Abstract:Laminitis is a common and painful condition of the equine foot and approximately 90% of cases are associated with insulin dysregulation (ID) that is a central feature of the common endocrine disorder equine metabolic syndrome (EMS) and occurs in a subset of animals with pituitary pars intermedia dysfunction. Additional features of EMS include obesity, altered circulating concentrations of adipokines (particularly adiponectin and leptin) and hypertriglyceridaemia. Obesity, ID, hypoadiponectinaemia, hyperleptina… Show more
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