“…In the basolateral membrane domain of various epithelial tissues a number of anion transport systems have been described dealing with bicarbonate and chloride movements: C1/HCO3 exchange [3,13,16], Na-coupled C1/HCO3 exchange [3,14,16,33,37], electrogenic Na-(HCO3)3 cotransport [2,5,9,12,16,17,37,44], passive rheogenic bicarbonate transfer [4,6] and C1 conductance [20,35]. There is evidence that in several cell types anions cross basolateral membranes by means of multiple pathways [13,28,33].…”