Sodium and water disturbances in patients with Sheehan's syndrome

Pham, Phuong‐Chi T.; Pham, Phuong-Anh T.; Pham, Phuong‐Thu T.

doi:10.1053/ajkd.2001.26918

Cited by 13 publications

(9 citation statements)

References 12 publications

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“…Taken together, we concluded that GC administration was necessary in the present case. Concomitant use of 3% saline was avoided because it may cause rapid correction of hyponatremia (10).…”

Section: Discussionmentioning

confidence: 99%

Incremental Increases in Glucocorticoid Doses May Reduce the Risk of Osmotic Demyelination Syndrome in a Patient with Hyponatremia due to Central Adrenal Insufficiency

Yoshioka¹,

Minami²,

Fujimoto³

et al. 2012

Intern. Med.

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A 50-year-old man was admitted to our hospital because of general malaise. Laboratory tests revealed severe hyponatremia (104 mEq/L), which was attributed to central adrenal insufficiency. To treat presumed central diabetes insipidus (CDI), we administered a small dose of hydrocortisone and gradually increased it to maintenance doses to prevent osmotic demyelination syndrome (ODS). Serum sodium levels did not increase more than 10 mEq/L/day and ODS did not occur. Thereafter, the patient was proven to have CDI. Incremental increases in glucocorticoid dose may reduce the risk of ODS for patients with hyponatremia due to central adrenal insufficiency, especially that complicated by CDI.

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“…Taken together, we concluded that GC administration was necessary in the present case. Concomitant use of 3% saline was avoided because it may cause rapid correction of hyponatremia (10).…”

Section: Discussionmentioning

confidence: 99%

Incremental Increases in Glucocorticoid Doses May Reduce the Risk of Osmotic Demyelination Syndrome in a Patient with Hyponatremia due to Central Adrenal Insufficiency

Yoshioka¹,

Minami²,

Fujimoto³

et al. 2012

Intern. Med.

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“…This woman was diagnosed through a generalized seizure, which was probably a result of hyponatremia. However, hyponatremia is a rare initial symptom of Sheehans syndrome (Pham et al, 2001). The particular vulnerability of the pituitary to postpartum blood loss is thought to relate in part to its considerable increase in size and vascularity during pregnancy.…”

Section: Discussionmentioning

confidence: 99%

Early Postpartum Hyponatremia in a Patient with Transient Sheehan's Syndrome

Munz

Seufert²,

Pg³

et al. 2004

Exp Clin Endocrinol Diabetes

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In modern day health care, Sheehan's syndrome is a rare disorder affecting the postpartum period. We present a case of a 33-year-old woman with atonic hemorrhage developing a transient Sheehan's syndrome associated with hyponatremia six days postpartum. Evaluation of cranial computer tomography and magnetic resonance imaging of the pituitary demonstrated normal finding. Immediate replacement therapy using sodium, chloride, hydrocortisone, fludrocortisone and levothyroxine revealed regression of the Sheehan's syndrome to complete recovery. The present report shows that Sheehan's syndrome can be associated with hyponatremia and illustrates the need to include hyponatremia as an initial symptom in the differential diagnosis of Sheehan's syndrome.

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“…ADH is released in response to effective volume depletion; consequently when hypothyroidism is encountered in the setting of complete pituitary failure there is often hyponatremia 2, 3. Alternatively, with myxedema, the ability of the kidney to handle a water load and concentrate urine can be impaired 4…”

Section: Hypothyroidism and Hyponatremiamentioning

confidence: 99%

Four nephrology myths debunked

Rachoin

Cerceo

2010

Journal of Hospital Medicine

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There are many controversial topics relating to renal disease in hospitalized patients. The aim of this review is to shed light on some important and often debated issues. Hypothyroidism, unlike myxedema, is not a cause of hyponatremia (although it can be sometimes seen in conjunction with the latter) and additional investigations should be done to determine its etiology. Sodium bicarbonate is effective for treatment of hyperkalemia primarily by enhancing renal potassium elimination rather than by translocating potassium into cells. Acetaminophen can be a cause of metabolic acidosis by causing 5‐oxoprolinuria. Furosemide (and sulfa containing diuretics) can safely be used in patients with an allergy to sulfa‐containing antibiotics (SCA). Journal of Hospital Medicine 2010;. © 2010 Society of Hospital Medicine.

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Sodium and water disturbances in patients with Sheehan's syndrome

Cited by 13 publications

References 12 publications

Incremental Increases in Glucocorticoid Doses May Reduce the Risk of Osmotic Demyelination Syndrome in a Patient with Hyponatremia due to Central Adrenal Insufficiency

Incremental Increases in Glucocorticoid Doses May Reduce the Risk of Osmotic Demyelination Syndrome in a Patient with Hyponatremia due to Central Adrenal Insufficiency

Early Postpartum Hyponatremia in a Patient with Transient Sheehan's Syndrome

Four nephrology myths debunked

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