“…In this study, ERS-related genes ( ATF6 , XBP-1 , GRP78 , CHOPα , and Eif2α ) and key proteins (XBP-1, GRP78, and Eif2α) were markedly upregulated in the HC group, but intestinal ERS was significantly alleviated in juvenile largemouth bass following the addition of SA and SB to the diet. Previous studies have demonstrated that SA and SB can ameliorate tissue damage by attenuating ERS in the brain, liver, and intestine of mice ( Hu et al., 2018 ; Wu et al., 2021 ; Zhang et al., 2016 ). However, few studies have examined the effect of adding SA and SB to the diet on ameliorating HC-induced intestinal ERS in fish.…”