Sociological Research of Information Needs of Pharmaceutical Employees

The domestic pharmaceutical market still lacks reparative drugs, which determines research on their creation as an urgent theoretical and applied task. In this regard, the expediency of developing the composition and technology for obtaining a polycomponent gel with a predictable positive effect on wound healing processes based on dermal biopolymers and a complex of biologically active substances of corn columns with stigmas is substantiated. The complex of technological studies carried out made it possible to establish the optimal composition and technology for obtaining a polycomponent gel. At the next necessary stage of pharmaceutical development, it was necessary to solve the issues of assessing the quality of the proposed composition of the polycomponent gel. The purpose of this study was to determine the criteria and methods for monitoring the quality indicators of a multicomponent reparative gel. The object of the study was experimental samples of a multicomponent gel obtained by introducing a thick extract of corn columns with stigmas into a collagen base. The quality of the polycomponent gel was assessed in accordance with the requirements of GPM.1.4.1.0008.15 "Ointments" of the State Pharmacopoeia IV edition according to the following criteria: "Description", pH, "Microbiological purity", authenticity and quantitative content of active substances. The indicator "Description" was evaluated organoleptically. The determination of the pH of the gel was carried out potentiometrically using a pH meter (Mettler Toledo, USA) according to GPM.1.2.1.0004.15 "Ionometry" directly in the gel sample. Microbiological purity was studied by the agar plate method in accordance with GPM.1.2.4.0002.15. The presence and quantitative determination of flavonoids in the developed gel was determined spectrophotometrically on a UV-1800 SHIMADZU spectrophotometer, Japan. As a result of the studies carried out, the criteria for the quality of a multicomponent gel of reparative action were studied and proposed. According to the "Description" indicator, the polycomponent gel is a homogeneous mass of light brown color with a pleasant fruity odor without impurities. It has been established that the polycomponent gel is characterized by a slightly alkaline pH value, which creates optimal conditions for the healing phase of the wound process. It is shown that the use of the method of differential spectrophotometry makes it possible to carry out a statistically significant qualitative and quantitative assessment of the content of flavonoids in the composition of a polycomponent gel.

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Topical Questions of Assessing the Quality of a Polycomponent Reparative Gel

Nikiforova

Melkonyan

D.V.

et al. 2023

Mediko-farmacevtičeskij žurnal "Pulʹs"

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Analysis of medical-ecological and socio-demographic factors of development of the coastal zone of the Sea of Azov

Arkhipova

Черногубова

Tarasova

2020

ICIGIS

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Coastal zones are integral natural and socio-economic territorial-water system, combined by a complex structure of interactions. Coastal geosystems are unique, rich in natural resources, which determines their attractiveness for industrial and residential, recreational, transport and other activities, but also makes them environmentally vulnerable. Sustainable development of the coastal zone is determined by the economic, social, and environmental components. The research area of interest is the coastal zone of the Sea of Azov (Rostov Region). The subject of the study is the state of medical and environmental safety of the territories. The purpose of the study is the analysis of medical-ecological and socio-demographic factors as the basis for sustainable development of the coastal zone of the Sea of Azov. A systematic approach has been implemented to assess the sustainable development of the coastal zone and to develop methods for analyzing and integrating heterogeneous data. Changes in the coastal zone were evaluated based on a comparative analysis of multizone satellite imagery with ground-based studies, data from thematic maps. For the analysis of medical and environmental safety, an author’s technique was used, combining traditional methods and geoinformation technologies based on ArcGis Desktop*. The environmental quality indicator was considered in terms of the impact on human health. Assessment of demographic security was carried out based on the coefficient of demographic well-being / prosperity of the territory. The incidence rate of malignant neoplasms was considered as a highly informative and socially significant indicator of the health status of the population. For analysis, we used the SSC RAS database for 2006-2016. A comprehensive analysis of the development factors of the coastal zone of the Sea of Azov showed significant problems in the studied region. The most attractive areas of the coastal zone of the Sea of Azov from the point of view of infrastructure development are at the same time subject to changes due to dangerous natural phenomena. Analysis of demographic indicators confirmed the presence of adverse demographic processes.

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Sociological Research of Information Needs of Pharmaceutical Employees

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Topical Questions of Assessing the Quality of a Polycomponent Reparative Gel

Topical Questions of Assessing the Quality of a Polycomponent Reparative Gel

Analysis of medical-ecological and socio-demographic factors of development of the coastal zone of the Sea of Azov

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