Socioeconomic status and its association with the risk of developing hip fractures: A region-wide ecological study

Reyes, Carlen; García-Gil, Maria; Elorza, Josep Maria; Fina-Aviles, F; Méndez-Boo, Leonardo; Hermosilla, Eduardo; Coma, Ermengol; Carbonell, Cristina; Medina, Manuel; Ramos, Rafael; Bolíbar, Bonaventura; Díez-Pérez, Adolfo; Prieto-Alhambra, Daniel

doi:10.1016/j.bone.2014.12.019

Cited by 30 publications

(26 citation statements)

References 34 publications

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“…Some of the articles found an increased incidence [20], [22], [23], [24], [25], [26], [27] while others found a decreased incidence of Hip fractures with low socioeconomic status [28], [29]. Some articles found an association with only some socioeconomic indicators [30], [33].…”

Section: Discussionmentioning

confidence: 99%

Risk Factors Associated With Hip Fractures among Adult People in Babylon City, Iraq

Al-Algawy

Baiee

Hasan

et al. 2019

Open Access Maced J Med Sci

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BACKGROUND: The fractures of hip joint considered as a serious problem in public health in the medical and socioeconomic issues, the incidence of the fracture neck femur is significantly increased with the increment of general population life span. AIM: The goal of this study is to highlight and focus on the most important risk factor for the hip fractures in our Babylon society, and to improve our understanding of the medical and social aspects of these predisposing factors. PATIENTS AND METHODS: A case-control study of older adults (above 60 years old). The study was done on tow samples. First, one consisting of 75 cases those having fracture neck femur considered as cases, and second sample as a control group, consisting of 150 people as a healthy control group having no fracture. A pre-tested questionnaire was prepared to collect data from both samples; the questionnaire included demographic data and information about potential risk factors of hip fracture. RESULTS: Most of the people in the study samples in both groups were, married women, housekeepers, illiterate and from urban dwellers. There was highly significant association between case-control groups regarding, Continuous using of medication such as cortisone which was found to be a potential risk factor of hip fracture (Unadjusted OR = 3.636), low income was positively associated risk factor of hip fracture in this study (OR = 2.377), low milk intake, low sun exposure, tobacco smoking were positively associated with this health problem (OR = 1.794), while physical exercise was protective factor (OR = 0.489). CONCLUSION: The highest risk factors associated with increased occurrence of hip fracture were using cortisone, Osteoporosis, tobacco smoking, consuming soft drinks, and less exposure to sunlight.

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Section: Discussionmentioning

confidence: 99%

Risk Factors Associated With Hip Fractures among Adult People in Babylon City, Iraq

Al-Algawy

Baiee

Hasan

et al. 2019

Open Access Maced J Med Sci

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“…The less marked relationship between deprivation and hip fracture incidence in women may in part, be explained by the stronger relationship between deprivation and obesity in women (37), as adiposity over the greater trochanter is thought to protect against hip fracture (38). Interestingly, a regional study in an urban population in Spain (2009-2012) demonstrated age-and sex-adjusted hip fracture risk was 10% lower in the most deprived as compared to the least deprived areas (12). However, this association was attenuated after adjustment for body mass index (BMI), suggesting that a higher prevalence of obesity in more deprived areas may have accounted for the inverse relationship observed.…”

Section: Discussionmentioning

confidence: 99%

“…Greater deprivation is associated with an increased hip fracture incidence in many countries including Australia (6), Canada (7), Portugal (8), Sweden (9) and the United States of America (USA) (10,11). In contrast, the reverse relationship has been reported in Spain where hip fracture risk was higher in the least deprived compared to most deprived areas, possibly explained by the protective effects of obesity for the hip (12). In the UK, a number of studies have identified an association between worsening deprivation and higher hip fracture incidence (13)(14)(15)(16); but this has not been consistently demonstrated albeit by studies of varying lengths (17,18).…”

Section: Introductionmentioning

confidence: 99%

The effect of social deprivation on hip fracture incidence in England has not changed over 14 years: an analysis of the English Hospital Episodes Statistics (2001–2015)

et al. 2017

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“…Level of education was considered as a surrogate for socioeconomic status, which may be associated with fracture risk [29]. Alcohol use was considered as present in women if there were at least 7 drinks/week and in men who drank at least 14 drinks/week.…”

Section: Methodsmentioning

confidence: 99%

Association of Plasma SDF-1 with Bone Mineral Density, Body Composition, and Hip Fractures in Older Adults: The Cardiovascular Health Study

et al. 2017

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Aging is associated with an increase in circulating inflammatory factors. One, the cytokine stromal cell-derived factor 1 (SDF-1 or CXCL12), is critical to stem cell mobilization, migration, and homing as well as to bone marrow stem cell (BMSC), osteoblast, and osteoclast function. SDF-1 has pleiotropic roles in bone formation and BMSC differentiation into osteoblasts/osteocytes, and in osteoprogenitor cell survival. The objective of this study was to examine the association of plasma SDF-1 in participants in the cardiovascular health study (CHS) with bone mineral density (BMD), body composition, and incident hip fractures. In 1536 CHS participants, SDF-1 plasma levels were significantly associated with increasing age (p < 0.01) and male gender (p = 0.04), but not with race (p = 0.63). In multivariable-adjusted models, higher SDF-1 levels were associated with lower total hip BMD (p = 0.02). However, there was no significant association of SDF-1 with hip fractures (p = 0.53). In summary, circulating plasma levels of SDF-1 are associated with increasing age and independently associated with lower total hip BMD in both men and women. These findings suggest that SDF-1 levels are linked to bone homeostasis.

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Socioeconomic status and its association with the risk of developing hip fractures: A region-wide ecological study

Cited by 30 publications

References 34 publications

Risk Factors Associated With Hip Fractures among Adult People in Babylon City, Iraq

Risk Factors Associated With Hip Fractures among Adult People in Babylon City, Iraq

The effect of social deprivation on hip fracture incidence in England has not changed over 14 years: an analysis of the English Hospital Episodes Statistics (2001–2015)

Association of Plasma SDF-1 with Bone Mineral Density, Body Composition, and Hip Fractures in Older Adults: The Cardiovascular Health Study

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