Abstract:the data are so highly skewed, it would be difficult for a general program such as Review Manager to produce a valid P value. In addition, their combined analysis of GO-BEFORE and GO-FORWARD trial data to evaluate the golimumab treatment effect is problematic given the heterogeneity between the 2 studies, including differences in patient populations and in criteria for inclusion in the MTX control arm.We acknowledge that the statistical methods were not described in detail in the original article because of sp… Show more
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