Sociodemographic Factors’ Influence on Adherence to Antihypertensive Medication

Marineci, Cristina Daniela

doi:10.31925/farmacia.2020.2.25

Cited by 2 publications

(1 citation statement)

References 24 publications

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“…We also quantified patients' adherence to medication, based on the superposition of drugs prescribed and those dispensed. Non-adherence to antihypertensive drugs reaches significant levels in Romanian patients, as previous studies revealed [19,24].…”

Section: Introductionmentioning

confidence: 78%

Patterns of Antihypertensive Drugs’ Use in Community Pharmacy; Drug Related Problems and Adherence to Medication Identified in a Retrospective Analysis of Prescriptions

Marineci¹

2020

FARMACIA

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Despite effective antihypertensive medication, arterial hypertension remains an important contributor to cardiovascular diseases, the main global cause of mortality. We performed a retrospective analysis of prescriptions containing antihypertensive drugs dispensed from two community pharmacies from Bucharest, Romania. In order to explore differences in prescriptions' trends, we analysed drugs dispensed in 2007 and 2017, evaluating the frequencies of the drugs used in monotherapy or in poly-therapy and the conformity with treatment guidelines available at the moment, the drug related problems and patients' adherence to medication, based on the superposition of drugs prescribed and those dispensed. We analysed 4635 prescriptions, from which 2332 were presenting at least HBP as diagnostic. 52.05% of the 2198 prescriptions from 2017 were for HBP, statistically significant compared to the 48.75% of the 2537 corresponding prescriptions from 2007. All the main antihypertensive drugs classes increased statistically significant in use from 2007 to 2017, except the angiotensin-converting enzyme inhibitors. Antihypertensive monotherapy decreased from 27.8% in 2007 to 19.7% in 2017 (p < 0.0001), which was in line with the updated recommendations that favoured combination therapy as being more efficacious. As to the drug regimen complexity, 11.5% of the prescriptions from 2007 and 18.6% of the prescriptions from 2017 contained antihypertensive drugs prescribed in a different manner from the one indicated in their officially endorsed monographs. We also found that in 2007, 10.94% of hypertensive patients didn't purchase all the medicines prescribed by the doctor, giving up part of their treatment. In 2017, the percentage of these nonadherent patients raised to 20.19%. We believe that pharmacist's interventions, including suggestions for simplification of the drug regimen, can increase the levels of adherence to medication, thus improving hypertensive patients' clinical outcomes. RezumatDeși medicația antihipertensivă este eficientă, hipertensiunea arterială (HTA) are o contribuție importantă la principala cauză de mortalitate la nivel global, bolile cardiovasculare. Am realizat o analiză retrospectivă a prescripțiilor destinate HTA, prescripții eliberate din două farmacii de comunitate din București, în perioade din doi ani diferiți (2007 și 2017), pentru a evalua tendințele de prescriere și utilizare a medicamentelor antihipertensive. Am determinat frecvențele generale de utilizare ale diferitelor antihipertensive atât în contextul monoterapiei cât și în cazul asocierilor, conformitatea cu ghidurile de tratament antihipertensiv în vigoare la momentele respective, problemele de terapie medicamentoasă și aderența pacienților la medicație, bazată pe concordanța dintre medicamentele prescrise și cele eliberate. Am analizat 4635 de prescripții, dintre care 2332 au avut cel puțin HTA ca diagnostic. 52,05% dintre cele 2198 de rețete din 2017 au fost pentru HTA, semnificativ statistic mai mult decât procentul prescripțiilor similare ...

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Section: Introductionmentioning

confidence: 78%

Patterns of Antihypertensive Drugs’ Use in Community Pharmacy; Drug Related Problems and Adherence to Medication Identified in a Retrospective Analysis of Prescriptions

Marineci¹

2020

FARMACIA

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Factors influencing medication adherence among hypertensive patients: A qualitative study

Nfor,

Warri

2024

Preprint

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Background: Medication non-adherence is a significant challenge in managing chronic diseases like hypertension. It often results in poor health outcomes and increased healthcare costs. Therefore, understanding patients' perspectives on barriers to adherence is vital in developing realistic interventions to promote medication adherence in hypertension and similar chronic diseases. Aim: This qualitative phenomenological study aimed to explore the experiences and barriers to adherence among hypertensive patients at the Bamenda Regional Hospital in Cameroon. Methods: Semi-structured interviews and a focus group discussion were conducted with 10 hypertensive patients aged 30 years and above, having difficulties adhering to their treatment plan. The interviews were transcribed and analyzed by thematic analysis using NVivo software. Results: Several key factors hindering adherence were identified from the themes including limited knowledge and awareness about hypertension and its treatment, negative attitudes and perceptions towards hypertension management, socioeconomic constraints limiting access to care, lack of social support, and poor patient-provider relationships. The study revealed a predominance of the biomedical model of care which often neglected patients' psychosocial needs. Conclusion: Addressing the barriers to adherence in hypertension patients demands a patient-centred approach to care. Such an approach must combine interventions for patient education and socioeconomic support. Social support systems, family involvement in care, and proper improved patient-provider collaboration also hold the potential to improve adherence. Recommendations: Based on the findings, this study recommends the implementation of targeted interventions such as patient education, socioeconomic support systems, family involvement in care, and training of care providers on patient-provider collaboration. Adopting a biopsychosocial care model is also crucial for promoting adherence.

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Sociodemographic Factors’ Influence on Adherence to Antihypertensive Medication

Cited by 2 publications

References 24 publications

Patterns of Antihypertensive Drugs’ Use in Community Pharmacy; Drug Related Problems and Adherence to Medication Identified in a Retrospective Analysis of Prescriptions

Patterns of Antihypertensive Drugs’ Use in Community Pharmacy; Drug Related Problems and Adherence to Medication Identified in a Retrospective Analysis of Prescriptions

Factors influencing medication adherence among hypertensive patients: A qualitative study

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