Socio-demographic, Clinical and Laboratory Features of Rotavirus Gastroenteritis in Children Treated in Pediatric Clinic

Abstract

Aim:The aim of work was presentation of several socio-demographic, clinical and laboratory characteristics of gastroenteritis caused by rotavirus.The examinees and methods:The examinees were children under the age of five years treated at the Pediatric Clinic due to acute gastroenteritis caused by rotavirus. Rotavirus is isolated by method chromatographic immunoassay by Cer Test Biotec.Results:From the total number of patients (850) suffering from acute gastroenteritis, feces test on bacteria, viruses. protozoa and fungi was positive in 425 (49.76%) cases. From this number the test on bacteria was positive in 248 (58.62%) cases, on viruses it was positive in 165 (39.0%), on protozoa in 9 (2.12%) cases and on fungi only one case. Rotavirus was the most frequent one in viral test, it was isolated in 142 (86.06%) cases, adenoviruses were found in 9 (5.45%) cases and noroviruses in only one case. The same feces sample that contained rotavirus and adenoviruses were isolated in five cases, whereas rotavirus with bacteria was isolated in the same feces sample in five cases. The biggest number of cases 62 (43.66%) were of the age 6-12 months, whereas the smallest number 10 (7.04%) cases were of the age 37-60 months. There were 76 (53.52%) of cases of male gender, from rural areas there were 81 (57.04%) cases and there were 58 (40.80%) cases during the summer period. Among the clinical symptoms the most prominent were diarrhea, vomiting, high temperature, whereas the different degree of dehydration were present in all cases (the most common one was moderate dehydration). The most frequent one was isonatremic dehydration in 91 (64.08%) cases, less frequent one was hypernatremic dehydration in 14 (9.85%) cases. The majority of cases (97.89%) had lower blood pH values, whereas 67 (47.17%) cases had pH values that varied from 7.16 -7.20 (curve peak), normal values were registered in only 3 (2.11%) cases. Urea values were increased in 45 (31.07%) cases (the maximum value was 26.5 mmol/L), whereas creatinine value was increased in 41 (28.87%) cases (maximum value was 302 mmol/L).Conclusion:The results show the high frequency of rotavirus infections in children hospitalized with acute gastroenteritis. Rotavirus may cause different dehydration degree with electrolyte, acid-base and other biochemical disorders. Preventing the infection caused by rotavirus is of a great importance.

A descriptive hospital based study of rotavirus diarrhoea in children aged 6 months to 3 years

“…Proportion of male and female patients were 53% and 47% respectively in a study done by Azemi M et al in Kosovo 7 . In our study we found that 40% of cases with rotavirus diarrhoea were seen from October-December and 31% from July-September.…”

“…Azemi M et al in 2012 also observed no electrolyte abnormality in 64.1% patients. Only 9.85% of patients suffered hypernatremia 7 .…”

“…In our study the consistency of stools was watery in 86% cases. Azemi M, et al observed that the stools were watery in the majority of cases 7 .…”

“…Similar results were seen in a study conducted by Azemi M, et al where the most dominant symptom was diarrhoea (98.6%) followed by vomiting (88%). The average duration of diarrhoea was 5 days 7 . In our study the consistency of stools was watery in 86% cases.…”

Prevalence of Rotavirus in Children with Acute Gastroenteritis, Seasonal Distribution, and Laboratory Findings in the Southeast of Turkey

“…When many rotavirus studies carried out nationally as well as internationally are examined, it is clearly seen that information about laboratory features is very limited. In a study in which childhood gastroenteritis were assessed, it was reported that the most common laboratory findings were metabolic acidosis (47.17%), hypernatremia (9.89%) and high level of urea (31.07%) (24). In a study done in Turkey, on the other hand, metabolic acidosis (3.5%) and prerenal failure (4.5%) were reported to be the most common laboratory findings (25).…”