Societal Aspects: Ethics

Lewis, Colin M.; Chitty, Lyn S.

doi:10.1007/978-94-017-9168-7_14

Cited by 1 publication

(1 citation statement)

References 60 publications

(80 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The potential for routinization of NIPT is high, given its similarity to existing normalized prenatal tests and especially because of the simplicity of the procedure. If NIPT is routinized, women may not be provided with adequate opportunity to decline testing, or may not receive sufficient information to make an informed decision [76, 81], and may ultimately feel disempowered, rather than empowered, by their choice.…”

Section: Discussionmentioning

confidence: 99%

Facilitating informed choice about non-invasive prenatal testing (NIPT): a systematic review and qualitative meta-synthesis of women’s experiences

Cernat

Freitas

Majid

et al. 2019

BMC Pregnancy Childbirth

View full text Add to dashboard Cite

BackgroundNon-invasive prenatal testing (NIPT) can be used to accurately detect fetal chromosomal anomalies early in pregnancy by assessing cell-free fetal DNA present in maternal blood. The rapid diffusion of NIPT, as well as the ease and simplicity of the test raises concerns around informed decision-making and the potential for routinization. Introducing NIPT in a way that facilitates informed and autonomous decisions is imperative to the ethical application of this technology. We approach this imperative by systematically reviewing and synthesizing primary qualitative research on women’s experiences with and preferences for informed decision-making around NIPT.MethodsWe searched multiple bibliographic databases including Ovid MEDLINE, EBSCO Cumulative Index to Nursing & Allied Health Literature (CINAHL), and ISI Web of Science Social Sciences Citation Index (SSCI). Our review was guided by integrative qualitative meta-synthesis, and we used a staged coding process similar to that of grounded theory to conduct our analysis.ResultsThirty empirical primary qualitative research studies were eligible for inclusion. Women preferred to learn about NIPT from their clinicians, but they expressed dissatisfaction with the quality and quantity of information provided during counselling and often sought information from a variety of other sources. Women generally had a good understanding of test characteristics, and the factors of accuracy, physical risk, and test timing were the critical information elements that they used to make informed decisions around NIPT. Women often described NIPT as easy or just another blood test, highlighting threats to informed decision-making such as routinization or a pressure to test.ConclusionsWomen’s unique circumstances modulate the information that they value and require most in the context of making an informed decision. Widened availability of trustworthy information about NIPT as well as careful attention to the facilitation of counselling may help facilitate informed decision-making.Trial registrationPROSPERO 2018 CRD42018086261.Electronic supplementary materialThe online version of this article (10.1186/s12884-018-2168-4) contains supplementary material, which is available to authorized users.

show abstract

Section: Discussionmentioning

confidence: 99%