Aims and objectives: To evaluate the enablers, barriers and impact that Communities of Practice has on novice nurses and students learning to become Registered Nurses. Background: Communities of Practice (CoP) have formed the basis for conceptualising the process of learning that occurs amongst groups of people within a place of work-a mainstay of healthcare practice. There is a dearth of literature that focuses specifically on the outcomes from student and novice engagement with existing Communities of Practice. Design: Systematic review and Metasynthesis Methods: Medline, PubMed, Embase, CINAHL, ProQuest, Scopus, and PsycINFO databases were accessed between 1997 and 2019. The screening and selection of studies were based on eligibility criteria and methodological quality assessment using the Critical Appraisal Skills Programme tool for qualitative research. Metasynthesis was grounded in the original experiences and collectively synthesised into meaningful themes. The review follows the PRISMA reporting guidelines and PRISMA checklist. Results: The findings highlight three major themes and included Enablers for successful CoP, Barriers to successful CoP, and Success in action as described by students and novice nurses. Discussion: We suggest successful CoP occur when safe and supported spaces ensure students and novices feel comfortable to experiment with their learning, and we emphasise the benefits of having more novice nurses situated within close proximity and under the direct influence of the established practices of more experienced or core group of peers. 2 Relevance to Clinical Practice: Communities of Practice that function successfully create an environment that prioritise the embedding of novices into the broader group. In so doing, students and novice nurses feel supported, welcomed, empowered, able to make the transition from student to colleague and novice nurse to more experienced nurse. It allows them to experiment with ever new ways of fulfilling the role, while aiding better clinical outcomes.