Social media is changing how those in the helping professions offer clinical, medical, or educational services, provide referrals, administer therapeutic interventions, and conduct research. Non-profits and government organizations working with vulnerable populations need to consider the possibility of ethical missteps when using social media. A comparison of Facebook strategies used with the National Youth in Transition Database (NYTD) program to engage and locate current and former youth in the foster care system was conducted. Facebook practices and strategies were examined based on the current National Association of Social Workers (NASW) Code of Ethics and the Association of Social Work Boards (ASWB) Standards for Technology and Social Work Practice. The ethical standards examined included obtaining consent, preserving confidentiality, verifying youth identity online, and avoiding disclosure of foster care affiliation. Findings provide valuable insight for further discussions around ethical standards in light of the rapidly changing uses of technology in social work. In addition, we illustrate guidelines and best practices used when adopting social media tools for interacting with vulnerable populations.