Social neural sensitivity as a susceptibility marker to family context in predicting adolescent externalizing behavior

Turpyn, Caitlin C.; Jorgensen, Nathan A.; Prinstein, Mitchell J.; Lindquist, Kristen A.; Telzer, Eva H.

doi:10.1016/j.dcn.2021.100993

Cited by 15 publications

(21 citation statements)

References 60 publications

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“…Overall, these results are consistent with literature linking greater neural reactivity in the subcortical reward network to behavior changes in different social environments 13,14,15 . However, the study did have several limitations to consider.…”

Section: Discussionsupporting

confidence: 91%

“…Conversely, those with lower reward response may be resilient in the face of negative influence but may also be less likely to experience benefits when in positive environments. Similar effects may also be found in a single direction; for example, greater sensitivity in reward regions of the brain in response to social reward or punishment modulates adolescent risk taking 13 and externalizing behavior 14 in negative environments, while other biological markers have been shown to modulate positive environments 15 . However, the link between reward susceptibility and social well-being within socially rich or impoverished environments has not yet been studied.…”

Section: Research Highlightsmentioning

confidence: 84%

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Neural sensitivity to social reward predicts social behavior and satisfaction in adolescents during the COVID-19 pandemic

Dziura¹,

McNaughton²,

Giacobbe³

et al. 2022

Preprint

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Neural reward network sensitivity in adolescence is proposed to differentially impact the effects of social environments on social outcomes. The COVID-19 pandemic provided an opportunity to test this hypothesis within a context of diminished in-person social interaction. We examined whether neural sensitivity to interactive social reward moderates the relationship between frequency of interactive or passive social activity and social satisfaction. Survey reports of frequency of interactions with friends, non-interactive social media use, feelings of social needs being met, and loneliness were gathered in 2020 during mandated precautions limiting in-person contact. A subset of participants previously participated in an fMRI study examining social interactive reward during a simulated peer interaction (Survey n = 76; Survey + fMRI n = 40). We found evidence of differential response to social context, such that adolescents with higher neural reward sensitivity had a strong positive association between frequency of interactive connections with friends and social needs met, while those with lower sensitivity showed no effect. Further, high reward sensitive adolescents reported higher levels of loneliness with increasing social media use, whereas low reward sensitive adolescents reported the opposite with the same behaviors. This indicates that youth with greater sensitivity to social interactive reward are more susceptible to negative effects of infrequent contact, whereas low reward sensitive adolescents are less susceptible and instead maintain social well-being through passive viewing of social content. These differential outcomes have implications for supporting youth during times of major social disruption as well as ensuring mental health and well-being more broadly.

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Section: Discussionsupporting

confidence: 91%

Section: Research Highlightsmentioning

confidence: 84%

Neural sensitivity to social reward predicts social behavior and satisfaction in adolescents during the COVID-19 pandemic

Dziura¹,

McNaughton²,

Giacobbe³

et al. 2022

Preprint

View full text Add to dashboard Cite

show abstract

“…For example, iron rich diets and supplements may decrease lead concentration in blood (Kordas, 2017). Similarly, selenium supplements may help to mitigate health effects related to mercury toxicity (Spiller et al., 2018). In research on psychosocial moderators of the link between pollutant exposure and adverse health outcomes, the associations between air pollution and stress biology in adolescents are stronger in youth who report experiencing more severe mental health difficulties (Miller et al., 2020; Miller et al., 2019).…”

Section: Introductionmentioning

confidence: 99%

“…In a recent study of newborn infants, Overfeld et al. (2020) found that postnatal enrichment was positively associated with early cognitive development only in infants with larger hippocampal volume. Across these studies, individuals with smaller hippocampal volume appear to be less sensitive to both the costs and the benefits associated with environmental support and adversity (Overfeld et al., 2020; Schriber et al., 2017; Whittle et al., 2011).…”

Section: Introductionmentioning

confidence: 99%

“…The brain is the central organ in perceiving and responding to environmental input (McEwen, 2012). Therefore, a growing body of research is examining brain-based measures of neurobiological sensitivity and vulnerability to social adversities (Guyer, 2020;Schriber & Guyer, 2016;Turpyn et al, 2021). Hippocampal volume is emerging from this literature as a potential neurobiological marker of sensitivity to context.…”

Section: Introductionmentioning

confidence: 99%

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Hippocampal volume indexes neurobiological sensitivity to the effect of pollution burden on telomere length in adolescents

Miller

Buthmann

Gotlib

2022

New Drctns Chld & Adlscnt

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Exposure to environmental pollutants has been associated with cellular aging in children and adolescents. Individuals may vary, however, in their sensitivity or vulnerability to the effects of environmental pollutants. Larger hippocampal volume has emerged as a potential index of increased sensitivity to social contexts. In exploratory analyses (N = 214), we extend work in this area by providing evidence that larger hippocampal volume in early adolescence reflects increased sensitivity to the effect of neighborhood pollution burden on telomere length (standardized β = -0.40, 95% CI[-0.65, -0.15]). In contrast, smaller hippocampal volume appears to buffer this association (standardized β = 0.02). In youth with larger hippocampal volume, pollution burden was indirectly associated with shorter telomere length approximately 2 years later through shorter telomere length at baseline (indirect standardized β = -0.25, 95% CI[-0.40, 0.10]). For these youth, living in high or low pollutionburdened neighborhoods may predispose them to develop shorter or longer telomeres, respectively, later in adolescence.

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Neural sensitivity to social reward predicts links between social behavior and loneliness in youth during the COVID‐19 pandemic

Dziura

McNaughton

Giacobbe

et al. 2023

Developmental Psychobiology

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Neural reward network sensitivity in youth is proposed to differentially impact the effects of social environments on social outcomes. The COVID‐19 pandemic provided an opportunity to test this hypothesis within a context of diminished in‐person social interaction. We examined whether neural sensitivity to interactive social reward moderates the relationship between a frequency of interactive or passive social activity and social satisfaction. Survey reports of frequency of interactions with friends, passive social media use, and loneliness and social satisfaction were gathered in 2020 during mandated precautions limiting in‐person contact. A subset of participants (age = 10–17) previously participated in a functional magnetic resonance imaging (fMRI) study examining social‐interactive reward during a simulated peer interaction (survey n = 76; survey + fMRI n = 40). We found evidence of differential response to social context, such that youth with higher neural reward sensitivity showed a negative association between a frequency of interactive connections with friends and a combined loneliness and social dissatisfaction component (LSDC) score, whereas those with lower sensitivity showed the opposite effect. Further, high reward sensitivity was associated with greater LSDC as passive social media use increased, whereas low reward sensitivity showed the opposite. This indicates that youth with greater sensitivity to social‐interactive reward may be more susceptible to negative effects of infrequent contact than their low reward‐sensitive counterparts, who instead maintain social well‐being through passive viewing of social content. These differential outcomes could have implications for supporting youth during times of major social disruption as well as ensuring mental health and well‐being more broadly.

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Social neural sensitivity as a susceptibility marker to family context in predicting adolescent externalizing behavior

Abstract: Highlights We examined brain function during anticipation of social reward and punishment. Neural sensitivity reflected increased susceptibility to negative family contexts. For youth high in sensitivity, family conflict predicted externalizing behavior.

Cited by 15 publications

References 60 publications

Neural sensitivity to social reward predicts social behavior and satisfaction in adolescents during the COVID-19 pandemic

Neural sensitivity to social reward predicts social behavior and satisfaction in adolescents during the COVID-19 pandemic

Hippocampal volume indexes neurobiological sensitivity to the effect of pollution burden on telomere length in adolescents

Neural sensitivity to social reward predicts links between social behavior and loneliness in youth during the COVID‐19 pandemic

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