Social Network and Coronary Artery Calcification in Asymptomatic Individuals

Kop, Willem J.; Berman, Daniel S.; Gransar, Heidi; Wong, Nathan D.; Miranda-Peats, Romalisa; White, Maria D; Shin, Magnolia; Bruce, Melissa; Krantz, David S.; Rozanski, Alan

doi:10.1097/01.psy.0000161201.45643.8d

Cited by 74 publications

(48 citation statements)

References 50 publications

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“…They also support behavior conducive to good health. With regard to somatic pathology, a lack of close personal relationships, reflected in being single or widowed, has been found to be associated with greater incidence of coronary artery calcification independent of age and coronary risk factors (Kop et al, 2005). Subjects with more extensive social networks have been shown to have greater antibody response to influenza vaccine (Pressman et al, 2005), and social participation and engagement have also been shown to be predictive of lesser dementia and cognitive decline in men and women who are more than 65 years of age (Kawachi & Berkman, 2001).…”

Section: Social Networkmentioning

confidence: 98%

Spirituality and recovery in 12-step programs: An empirical model

Galanter

2007

Journal of Substance Abuse Treatment

102

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Section: Social Networkmentioning

confidence: 98%

Spirituality and recovery in 12-step programs: An empirical model

Galanter

2007

Journal of Substance Abuse Treatment

102

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“…Correlating with human participants, research has shown that subjects with poor social support have exaggerated blood pressure and heart rate responses to stressful situations with a remarkably slow recovery time [22]. These same set of people also experience autonomic imbalances [23], exaggerated inflammation [24], increased calcification in the coronary arteries [25], and significant hypertrophy of the left ventricle [26]. These evidences support the hypothesis that social isolation contributes to CVD morbidity and mortality.…”

Section: Reviewmentioning

confidence: 99%

The Pathophysiology of Perceived Social Isolation: Effects on Health and Mortality

Bhatti¹,

Haq²

2017

Cureus

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Perceived social isolation (PSI) is a deficit in normal human social interaction, which has been associated with negative health outcomes. However, the precise mechanisms through which PSI influences human health are not fully known. This review aims at bringing out what is known about these pathways through which social isolation affects human health. We searched PubMed, Medical Literature Analysis and Retrieval System Online (MEDLINE), Excerpta Medica dataBASE (EMBASE), Psychological Information Database (PsycINFO), and Cochrane Library in addition to secondary references from primary journal articles for the most relevant and recent information concerning the research topic. The keywords used were perceived social isolation, loneliness, health outcomes, cardiovascular effects, neuroendocrine effects, depression, and cognitive decline, in animal and human populations. There are clear linkages between PSI and the cardiovascular system, neuroendocrine system, and cognitive functioning. PSI also leads to depression, cognitive decline, and sleep problems. The mechanisms through which PSI causes these effects are neural, hormonal, genetic, emotional, and behavioral. The effects of PSI on health are both direct and indirect. There is a complex interconnected network of pathways through which PSI negatively influences health. These hypothetical pathways using which the effects of PSI have been explained form the base on which further analyses can be carried out.

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“…Likewise, social relationships have been linked to the development [16,17] and progression [18][19][20][21] of cardiovascular disease [22]-a leading cause of death globally. Therefore, synthesis of the current empirical evidence linking social relationships and mortality, along with clarifications of potential moderators, may be particularly relevant to public health and clinical practice for informing interventions and policies aimed at reducing risk for mortality.…”

Section: Introductionmentioning

confidence: 99%