Social Distancing and Quarantine as COVID-19 Control Remedy

Ahmad, Adeel; Hussaan, Muhammad; Fatima, Batool; Rehman, Nagina; Yaqoob, Samina; Kausar, Humaira

doi:10.1201/9781003283607-7

Cited by 2 publications

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“…Due to its transmissibility, individuals must avoid being present in public. This is the way World Health Organization (WHO) controlled the SARS and MERS breakouts 11,12 . Coronaviruses, classified into four groups, can cause a spectrum of illnesses from mild to severe.…”

Section: Hla Immune Response and Susceptibility To Covid‐19mentioning

confidence: 99%

“…This is the way World Health Organization (WHO) controlled the SARS and MERS breakouts. 11 , 12 Coronaviruses, classified into four groups, can cause a spectrum of illnesses from mild to severe. Attention must be given to the diverse dispersion of these viruses in different countries based on their climates, and their genetic makeup can easily evolve through various mutations.…”

Section: Hla Immune Response and Susceptibility To ...mentioning

confidence: 99%

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The role of HLA genetic variants in COVID‐19 susceptibility, severity, and mortality: A global review

Hoseinnezhad,

Soltani,

Ziarati

et al. 2024

Clinical Laboratory Analysis

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BackgroundThe COVID‐19 pandemic has had a profound global impact, with variations in susceptibility, severity, and mortality rates across different regions. While many factors can contribute to the spread and impact of the disease, specifically human leukocyte antigen (HLA) genetic variants have emerged as potential contributors to COVID‐19 outcomes.MethodsIn this comprehensive narrative review, we conducted a thorough literature search to identify relevant studies investigating the association between HLA genetic variants and COVID‐19 outcomes. Additionally, we analyzed allelic frequency data from diverse populations to assess differences in COVID‐19 incidence and severity.ResultsOur review provides insights into the immunological mechanisms involving HLA‐mediated responses to COVID‐19 and highlights potential research directions and therapeutic interventions. We found evidence suggesting that certain HLA alleles, such as HLA‐A02, may confer a lower risk of COVID‐19, while others, like HLA‐C04, may increase the risk of severe symptoms and mortality. Furthermore, our analysis of allele frequency distributions revealed significant variations among different populations.ConclusionConsidering host genetic variations, particularly HLA genetic variants, is crucial for understanding COVID‐19 susceptibility and severity. These findings have implications for personalized treatment and interventions based on an individual's genetic profile. However, further research is needed to unravel the precise mechanisms underlying the observed associations and explore the potential for targeted therapies or preventive measures based on HLA genetic variants.

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Section: Hla Immune Response and Susceptibility To Covid‐19mentioning

confidence: 99%

Section: Hla Immune Response and Susceptibility To ...mentioning

confidence: 99%

The role of HLA genetic variants in COVID‐19 susceptibility, severity, and mortality: A global review

Hoseinnezhad,

Soltani,

Ziarati

et al. 2024

Clinical Laboratory Analysis

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Problems of Falsification of Medicinal products in the conditions of the COVID-19 Pandemic: Adaptation of Ukrainian legislation to the norms of the European Union

Rizak,

Heiko,

Dovzhuk

et al. 2023

RJPT

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The problem of distribution of low-quality medicinal products in Ukraine has become especially relevant against the background of the spread of the COVID-19 pandemic. The challenge to the national medical system became more tangible, as the fight against the virus and quarantine restrictions became heavy psychological blows for patients who sought appropriate treatment in an unofficial way. The purpose of the article is to analyze the problem of falsification of medicines in the conditions of a pandemic and to develop development models against the background of the study of European legislative norms. General scientific methods (synthesis, analysis, induction and deduction) became the main methods for writing the article. The methods of content analysis, systematic review of scientific literature, SMART and FINER principles were also used. The results highlighted one of the most important problems of the distribution of falsified and unlicensed drugs during the spread of COVID-19 - the semi-legal activity of pharmacies that work exclusively in the field of online sales. The requirements for their activities are quite loyal, and the distribution of low-quality or uncertified medicinal products is punished only administratively. The possibility of using European (primarily German) experience to counter the distribution of falsified medicines was discussed. Attention was also drawn to the geopolitical factor in the fight against COVID-19 – the use of the Russian vaccine “SPUTNIK V”, which in the conditions of Russian aggression can be assessed as a hybrid threat. The problematic nature of using this vaccine has been demonstrated, given the secrecy of the mechanism of conducting experiments. Resolutions of the European regulatory bodies allowed Ukrainian doctors not to use this vaccine either. This episode can be considered a positive moment of using European experience to establish medical rules for work in Ukraine. The conclusions note the need to reform Ukrainian legislation, take into account the European experience and harmonize with European regulations on the circulation of medical drugs. Such a step will make it possible to face modern challenges and significantly complicate the entry of counterfeit medicines into Ukraine.

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Social Distancing and Quarantine as COVID-19 Control Remedy

Cited by 2 publications

References 0 publications

The role of HLA genetic variants in COVID‐19 susceptibility, severity, and mortality: A global review

The role of HLA genetic variants in COVID‐19 susceptibility, severity, and mortality: A global review

Problems of Falsification of Medicinal products in the conditions of the COVID-19 Pandemic: Adaptation of Ukrainian legislation to the norms of the European Union

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