Social competence in schizophrenia: Premorbid adjustment, social skill, and domains of functioning

Mueser, Kim T.; Bellack, Alan S.; Morrison, Randall L.; Wixted, John T.

doi:10.1016/0022-3956(90)90024-k

Cited by 142 publications

(66 citation statements)

References 35 publications

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“…Consistent with prior research, participants with psychotic disorders were less likely to be sexually active, possibly due to greater social impairments and psychotic symptoms (e.g., paranoia, disorganization, odd behavior) (Mueser, Bellack, Morrison, & Wixted, 1990). Yet, these problems do not eliminate desire for sexual contact.…”

Section: Discussionsupporting

confidence: 57%

Psychiatric and Psychosocial Correlates of Sexual Risk Behavior among Adults with Severe Mental Illness

Meade

Sikkema

2006

Community Ment Health J

105

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Persons with severe mental illness (SMI) are disproportionately affected by HIV/AIDS. This study examined multivariate correlates of sexual risk among 152 adults with SMI receiving outpatient psychiatric treatment. Structured interviews assessed psychiatric, psychosocial, and behavioral risk factors. The majority was sexually active (65%), and many reported unprotected intercourse (73%), multiple partners (45%), and sex trading (21%) in the past year. Logistic regression models found that sexual behaviors were differentially associated with non-psychotic disorder, psychiatric symptoms, substance abuse, childhood sexual abuse, romantic partnership, and social support (all ps < .05). Findings underscore the need for targeted HIV prevention interventions that address psychiatric and psychosocial risk factors.

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Section: Discussionsupporting

confidence: 57%

Psychiatric and Psychosocial Correlates of Sexual Risk Behavior among Adults with Severe Mental Illness

Meade

Sikkema

2006

Community Ment Health J

105

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“…Follow-back studies of school records, retrospective studies with patients and prospective studies of children of mothers suffering from schizophrenia have consistently found a greater frequency of premorbid deficits in social and occupational functioning for men than women (McGlashan and Mueser et al, 1990a;Moldin, 2000). This was also shown by the Israeli conscript study among probands aged 16 to 17 years (Weiser et al, 2000).…”

Section: Promorbid Functioning (Domain 4)mentioning

confidence: 99%

Schizophrenia: do men and women suffer from the same disease?

Häfner¹

2002

Rev. psiquiatr. clín.

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This article reviews the literature on normal brain development and behavioural development in men and women as well as on aetiological risk factors for schizophrenia, such as pre-, peri-and postnatal complications.The male-female comparisons of age and type of onset, symptomatology, course and outcome were based on a population-based sample of 232 first illness episodes -the ABC Schizophrenia Study sample. The probands were assessed using the IRAOS interview and other instruments retrospectively at first admission and prospectively at six cross sections over five years after first contact. A representative subsample of 130 first admissions or 115 first illness episodes were compared with 130 controls, matched by age, sex and area of residence.Women, 3 to 4 years older than men at illness onset, showed a second peak of onsets in age group 45 to 50 years. After animal experiments and a controlled clinical study this finding was explained by a protective effect of oestrogen persisting until menopause. The underlying neurobiological mechanism consisted in a sensitivity reducing effect of oestrogen on D2 receptors in the brain. The effect of oestrogen, meanwhile confirmed in randomised control trials, also includes genomic effects as well as interactions with free-radical detoxifying systems, thus demonstrating the neuroprotective capabilities of oestrogen.Postmenopausal schizophrenia was more frequent and more severe in women. Men fell ill more frequently and more severely at young age and less frequently and more mildly later in life. Illness course, too, was more unfavourable in postmenopausal women than in their male peers.The protective effect of oestrogen in women depended on the degree of their predisposition to the illness: the higher the familial load for schizophrenia, the weaker the protection by oestrogen. The more favourable illness course in premenopausal women resulted from their higher level of social development at illness onset -determined by their higher age at onset -and from their socially more adaptive behaviour. The illness behaviour of young men showed a significant excess of socially negative behaviours with an unfavourable impact on their early illness course. In contrast, older men were socially better adjusted. With genetic and morphological findings considered the subtypes of schizophrenia did not differ between men and women.Gender differences in symptomatology and course of schizophrenia obviously are not explained by differences in the disease process. They seem to be determined by a complex pattern of interaction between disease variables, hormonal and behavioural differences and their consequences for age at onset and illness course.

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“…Previous research has suggested that women with schizophrenia have a milder course of illness than men (1)(2)(3). Various factors have been proposed to account for this sex difference hypothesis including psychosocial differences, older age of onset for women, and differences in premorbid developmental achievement (4)(5)(6).…”

mentioning

confidence: 99%

Sex differences in schizophrenia and other psychotic disorders: a 20-year longitudinal study of psychosis and recovery

Grossman

Harrow

Rosen

et al. 2008

Comprehensive Psychiatry

143

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This longitudinal study was designed to provide data on sex differences in the course of illness in schizophrenia and other psychotic disorders. Ninety-seven participants (43 women and 54 men) were assessed during index hospitalization when they were in the acute phase of illness, and then reassessed prospectively at 6 consecutive followups over a 20 year period. Patients were evaluated by a series of standardized measures on many aspects of illness including the presence of psychosis, global outcome, and rate of recovery. When women were compared to men in this sample, the data demonstrated a lower percentage of psychotic activity for women over the course of illness (significant at the 7.5 and 20 year followups), and a significant improvement in psychotic activity over 20 years for women (p<.05), but not for men. Additionally, women showed significantly better global functioning (p<.05) at 3 of the 6 followups (the 2, 7.5, and 10-year followups). Significantly higher percentages (p<.05) of women were in recovery at 2 of the 6 followup years (the 2 and 10-year followups). Cumulatively, 61% of the women with schizophrenia showed a period of recovery at some point during the 20 year period, compared to 41% of the men. The sex difference patterns were similar for patients with schizophrenia and for those with other types of psychotic disorders. Sex differences in this sample were specifically not attributable to differences in age of onset or premorbid developmental achievements.

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Social competence in schizophrenia: Premorbid adjustment, social skill, and domains of functioning

Cited by 142 publications

References 35 publications

Psychiatric and Psychosocial Correlates of Sexual Risk Behavior among Adults with Severe Mental Illness

Psychiatric and Psychosocial Correlates of Sexual Risk Behavior among Adults with Severe Mental Illness

Schizophrenia: do men and women suffer from the same disease?

Sex differences in schizophrenia and other psychotic disorders: a 20-year longitudinal study of psychosis and recovery

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