Rapid advances in technology for highly automated vehicles (HAVs) have raised concerns about coexistence of HAVs and human road users. Although there is a long tradition of research into human road user interactions, there is a lack of shared models and terminology to support cross-disciplinary research and development towards safe and acceptable interaction-capable HAVs. Here, we review the main themes and findings in previous theoretical and empirical interaction research, and find large variability in perspectives and terminologies. We unify these perspectives in a structured, cross-theoretical conceptual framework, describing what road traffic interactions are, how they arise, and how they get resolved. Two key contributions are: (1) a stringent definition of "interaction", as "a situation where the behaviour of at least two road users can be interpreted as being influenced by the possibility that they are both intending to occupy the same region of space at the same time in the near future", and (2) a taxonomy of the types of behaviours that road users exhibit in interactions. We hope that this conceptual framework will be useful in the development of improved empirical methodology, theoretical models, and technical requirements on vehicle automation. Relevance to human factors/Relevance to ergonomics theory Smooth interactions with other road users-human or automated-is central to human safety, efficiency and satisfaction in road traffic. This paper ties together previously disparate theoretical and empirical work on road traffic interactions into a single conceptual theoretical framework.