Social and visual function in nystagmus

Pilling, Rachel; Thompson, John R.; Gottlob, Irène

doi:10.1136/bjo.2005.070045

Cited by 70 publications

(50 citation statements)

References 21 publications

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“…Many individuals with nystagmus will adopt an abnormal head posture to position their eyes where the nystagmus is least 3. Recent research estimates the prevalence of nystagmus to be 24/10 0004 and the impact of nystagmus is significant, with visual functioning scores in nystagmus worse than other visual disease such as age-related macular degeneration 5…”

Section: Introductionmentioning

confidence: 99%

Living with nystagmus: a qualitative study

2012

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Background/aims To identify aspects of daily living affected by nystagmus. Methods Semistructured interviews were conducted at the University of Leicester, UK with participants with acquired and infantile nystagmus. In total 21, participants were purposively sampled and recruited. Transcript analysis was conducted using constant comparative technique, based upon the grounded theory, to identify specific areas of living affected by nystagmus.

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Section: Introductionmentioning

confidence: 99%

Living with nystagmus: a qualitative study

2012

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“…1,2 Functional impairment in daily vision-related activities, assessed using the VF-14, is of a magnitude similar to that of patients with age-related macular degeneration. 3 INS is associated with decreased visual acuity due to associated sensory system deficits, amblyopia, or ametropia and is a direct result of the inability to maintain stable foveal vision. In a recent study of 224 adult patients with INS, mean visual acuity was 0.4 logMAR (20/50) in the idiopathic group, 0.7 logMAR (20/100) in the albinism group, and 0.6 logMAR (20/ 80) in the ONH and ocular disease group.…”

mentioning

confidence: 99%

Visual Acuity Development of Children with Infantile Nystagmus Syndrome

Bilonick

Felius

et al. 2011

Invest. Ophthalmol. Vis. Sci.

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“…The optokinetic as well as the vestibular system are involved in producing this involuntary, conjugate jerk nystagmus. However, nystagmus is mostly a pathology of the oculomotor system, resulting in several quality of life affecting issues, such as loss of visual acuity, decreased motion perception, and postural control problems (Dell ' Osso, 1991 ;Bedell , 1992 ;Pilling et al , 2005 ).…”

Section: Types Of Human Eye Movement Disordersmentioning

confidence: 99%

“…Pathological forms of eye movements such as infantile nystagmus entail inconvenient side effects such as reduced visual acuity (Dell ' Osso, 1991 ) or decreased motion perception (Bedell , 1992 ) along with general decrease in quality of life (Pilling et al , 2005 ).…”

Section: Introductionmentioning

confidence: 99%

Application of zebrafish oculomotor behavior to model human disorders

Maurer

Huang²

2011

Revneuro

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To ensure high acuity vision, eye movements have to be controlled with astonishing precision by the oculomotor system. Many human diseases can lead to abnormal eye movements, typically of the involuntary oscillatory eye movements type called nystagmus. Such nystagmus can be congenital (infantile) or acquired later in life. Although the resulting eye movements are well characterized, there is only little information about the underlying etiology. This is in part owing to the lack of appropriate animal models. In this review article, we des cribe how the zebrafi sh with its quick maturing visual system can be used to model oculomotor pathologies. We compare the characteristics and assessment of human and zebrafi sh eye movements. We describe the oculomotor properties of the zebrafi sh mutant belladonna , which has non-crossing optical fi bers, and is a particularly informative model for human ocu lomotor deficits. This mutant displays a reverse optokinetic response, spontaneous oscillations that closely mimic human congenital nystagmus and abnormal motor behavior linked to circular vection.

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Social and visual function in nystagmus

Cited by 70 publications

References 21 publications

Living with nystagmus: a qualitative study

Living with nystagmus: a qualitative study

Visual Acuity Development of Children with Infantile Nystagmus Syndrome

Application of zebrafish oculomotor behavior to model human disorders

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