“…Obermiller (1913) and Stiuhmer (1919) state that there may be no pathological changes in arsenical encephalopathy other than cerebral congestion and oedema. The characteristic lesion, however, in this condition is multiple plugged capillaries with petechial haemorrhages and surrounding necrosis and demyelination (Russell, 1937;Strauss and Globus, 1930;Alpers, 1928).…”