SNPs in splicing region and miRNA binding region of Bos taurus TREM-1 gene reveals its association with mastitis
N. S. Pandupuspitasari,
F. A. Khan,
A. Setiaji
et al.
Abstract:Proper splicing is important for the functioning of a gene, and any interruption in splicing causes several deleterious events. Triggering receptors present on myeloid cells, TREM-1, are implicated in inflammation and act as amplifiers by mediating the release of proinflammatory chemokines and cytokines in response to fungal and bacterial infections. In bovines, mastitis is an inflammatory disease in which mammary gland inflammation is generally caused by bacteria. We found rs109937179 and rs208224995 SNPs in … Show more
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