Snoring and carotid artery intima‐media thickness

Deeb, Robert; Judge, Paul D.; Peterson, Ed; Lin, Judith C.; Yaremchuk, Kathleen

doi:10.1002/lary.24527

Cited by 22 publications

(20 citation statements)

References 16 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Self-reported snoring has been shown to be correlated to changes in arterial wall morphology; a few studies evaluate the presence of carotid artery IMT in a population of snorers, and show a correlation between the two phenomena [29,30].…”

Section: Discussionmentioning

confidence: 97%

Association between self-reported snoring and arterial stiffness: data from the Brisighella Heart Study

et al. 2015

View full text Add to dashboard Cite

The correlation of both obstructive sleep apnoea syndrome (OSAS) and snoring with cardiovascular risk is well known, but its investigation is complex and not suitable for studying large cohorts of subjects. Thus, we prospectively evaluated 1476 non-pharmacologically treated subjects selected from the last survey of the Brisighella Heart Study. Snoring and sleep apnoea were investigated asking the subjects if they were aware of snoring during the night, and if this was associated with episodes of apnoea. A full set of clinical and laboratory parameters were evaluated, while augmentation index (AIx), and pulse wave velocity (PWV) were recorded with the Vicorder(®) apparatus. A logistic regression analysis identifies as main independent predictors of AIx age (OR 1.058, 95% CI 1.043-1.065, p < 0.001), Body Mass Index (OR 1.046, 95% CI 1.014-1.079, p = 0.005), and apolipoprotein B (OR 1.014, 95% CI 1.004-1.023, p = 0.001). The main independent predictors of PWV are snoring (OR 1.215, 95% CI 1.083-1.390, p < 0.001), and snoring with apnoea (OR 1.351, 95% CI 1.135-1.598, p = 0.014), age (OR 1.078, 95% CI 1.052-1.089, p < 0.001), serum uric acid [SUA] (OR 1.093, 95% CI 1.026-1.151, p < 0.001) and mean arterial pressure (OR 1.042, 95% CI 1.024-1.056, p < 0.001). In conclusion, in our cohort of overall healthy subjects, self-reported snoring and sleep apnoea are independently associated with a higher PVW, and AIx is statistically significantly higher in snorers with or without sleep apnoea than in non-snorers. Body Mass Index and apolipoprotein B are associated with AIx, while SUA and mean arterial pressure are related to PWV.

show abstract

Section: Discussionmentioning

confidence: 97%

Association between self-reported snoring and arterial stiffness: data from the Brisighella Heart Study

et al. 2015

View full text Add to dashboard Cite

show abstract

“…In a study of snorers and nonsnorers with only mild, nonhypoxic obstructive sleep apnea (OSA) syndrome, in which patients underwent polysomnography with quantification of snoring, heavy snoring was significantly associated with carotid atherosclerosis but not with femoral atherosclerosis . A previous study showed a relationship between primary snoring and intima‐media thickening of the carotid artery . Patients who identified themselves as snoring all of the time or most of the time in the past 4 weeks were found to have increased intima‐media thickening along several points of the carotid artery.…”

Section: Introductionmentioning

confidence: 88%

Snoring and carotid artery disease: A new risk factor emerges

et al. 2018

Self Cite

View full text Add to dashboard Cite

show abstract

“…et al (2011) проведено первое экспериментальное исследование, в котором показано, что вибрация вызывает эндотелиальную дисфункцию в каротидных артериях, чем и объяс няется развитие каротидного атеросклероза у лиц с храпом [42]. С тех пор гипотеза, что храп являет ся потенциальным фактором повреждения артери альной стенки и прогрессирования атеросклероза каротидных артерий, продолжает активно изучать ся [43][44][45].…”

Section: дискуссииunclassified

Bronchial asthma, wheezing, flatter: probable relationships

Абросимов

2017

Pulʹmonologiâ (Mosk.)

View full text Add to dashboard Cite

ДискуссииБронхиальная астма (БА) является одним из широко распространенных заболеваний. В соответствии с со временными представлениями БА -это хроничес кое персистирующее воспалительное заболевание, ведущее к структурным изменениям и ремоделиро ванию дыхательных путей (ДП). В понятие «ремо делирование» включены следующие основные ком поненты: гипертрофия гладких мышц, гиперплазия бокаловидных клеток, субэпителиальный (субба зальный) фиброз и ангиогенез [1][2][3][4][5]; развитие брон хиальной гиперреактивности [6].Хронический воспалительный процесс, ремоде лирование ДП, бронхиальная гиперреактивность, бронхиальная обструкция определяют характерные клинические симптомы БА -свистящие хрипы, ка шель, диспноэ [7][8][9], причем свистящее дыхание относится к наиболее частым из них. Так, по данным эпидемиологического исследования ECRHS (Euro pean Community Respiratory Health Survey) о распрост раненности симптомов БА среди лиц (мужчин и жен щин) 20-44 летнего возраста приступы удушья встречаются в среднем у 9,7 %, а свистящее дыха ние -у 32,0 % больных [10]. По результатам эпиде миологического исследования SAPALDIA свистя щие хрипы выявлены у 1 360 (14 %) лиц общей популяции из 9 651 обследованного. У 168 (75 %) из 225 больных БА свистящие хрипы являлись самым распространенным симптомом [11].В большинстве сообщений, включая доклад ра бочей группы GINA (Глобальная стратегия лечения и профилактика бронхиальной астмы, 2015), указы вается, что свистящее дыхание (wheezing) является одним из ключевых диагностических критериев БА [12][13][14]. У больных БА проведен анализ парамет ров легочных звуков в сопоставлении с данными ле гочных функций. Сделано заключение, что оценка легочных звуков может успешно применяться в ка честве биомаркера БА AbstractWheezing is the most common clinical sign and one of the key diagnostic criteria of asthma. Pathophysiology of wheezing is not fully recognized. A theory of hemodynamic flatter is widely adopted. Effects of vibration are actively investigated in patients with snore and obstructive sleep apnea. Vibration can contribute to the upper airway inflammation and endothelial dysfunction in snoring patients. Therefore, the flatter (vibration) effect could be the key mechanism of wheezing in asthma patients and could promote similar changes in the lower airway microvasculature. Recently, CPAP therapy has been shown to reduce asthma symptoms and bronchial hyperresponsiveness and acts as a mechanical bronchodilator is patients with asthma without sleep associated breathing disorders.

show abstract

Snoring and carotid artery intima‐media thickness

Abstract: 3b.

Cited by 22 publications

References 16 publications

Association between self-reported snoring and arterial stiffness: data from the Brisighella Heart Study

Association between self-reported snoring and arterial stiffness: data from the Brisighella Heart Study

Snoring and carotid artery disease: A new risk factor emerges

Bronchial asthma, wheezing, flatter: probable relationships

Contact Info

Product

Resources

About