SNMMI/ASNC/SCCT Guideline for Cardiac SPECT/CT and PET/CT 1.0

Dorbala, Sharmila; Carli, Marcelo F. Di; Delbeke, Dominique; Abbara, Suhny; DePuey, E. Gordon; Dilsizian, Vasken; Forrester, Joey; Janowitz, Warren R.; Kaufmann, Philipp A.; Mahmarian, John J.; Moore, Stephen; Stabin, Michael G.; Shreve, Paul

doi:10.2967/jnumed.112.105155

Cited by 190 publications

(141 citation statements)

References 129 publications

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“…When considered with the reported benefits of CTAC in improving the sensitivity and Full paper: Comparison of dose and risk of CTAC and radiopharmaceutical for MPI BJR specificity, it can be said that the reported benefits of attenuation and scatter correction using CT benefits do outweigh the risks. [33][34][35] A comparison of doses from the CTAC acquisitions showed some interesting findings. The protocol from the Siemens Symbia T6 gave the lowest E; this was significantly different to the protocols from the Philips Precedence and GE Hawkeye 4 slice systems (paired t-test, p , 0.05).…”

Section: Discussionmentioning

confidence: 99%

Comparison of effective dose and lifetime risk of cancer incidence of CT attenuation correction acquisitions and radiopharmaceutical administration for myocardial perfusion imaging

Tootell

Szczepura²,

Hogg³

2014

BJR

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Cite this article as: Tootell AK, Szczepura K, Hogg P. Comparison of effective dose and lifetime risk of cancer incidence of CT attenuation correction acquisitions and radiopharmaceutical administration for myocardial perfusion imaging. Br J Radiol 2014;87:20140110. FULL PAPERComparison of effective dose and lifetime risk of cancer incidence of CT attenuation correction acquisitions and radiopharmaceutical administration for myocardial perfusion imaging Objective: To measure the organ dose and calculate effective dose from CT attenuation correction (CTAC) acquisitions from four commonly used gamma camera single photon emission CT/CT systems. Methods: CTAC dosimetry data was collected using thermoluminescent dosemeters on GE Healthcare's Infinia™ Hawkeye™ (GE Healthcare, Buckinghamshire, UK) four-and single-slice systems, Siemens Symbia™ T6 (Siemens Healthcare, Erlangen, Germany) and the Philips Precedence (Philips Healthcare, Amsterdam, Netherlands). Organ and effective dose from the administration of 99m Tc-tetrofosmin and 99m Tc-sestamibi were calculated using International Commission of Radiological Protection reports 80 and 106. Using these data, the lifetime biological risk was calculated. Results: The Siemens Symbia gave the lowest CTAC dose (1.8 mSv) followed by the GE Infinia Hawkeye single-slice (1.9 mSv), GE Infinia Hawkeye four-slice (2.5 mSv) and Philips Precedence v. 3.0. Doses were significantly lower than the calculated doses from radiopharmaceutical administration (11 and 14 mSv for 99m Tc-tetrofosmin and 99m Tc-sestamibi, respectively). Overall lifetime biological risks were lower, which suggests that using CTAC data posed minimal risk to the patient. Comparison of data for breast tissue demonstrated a higher risk than that from the radiopharmaceutical administration. Conclusion: CTAC doses were confirmed to be much lower than those from radiopharmaceutical administration. The localized nature of the CTAC exposure compared to the radiopharmaceutical biological distribution indicated dose and risk to the breast to be higher. Advances in knowledge: This research proved that CTAC is a comparatively low-dose acquisition. However, it has been shown that there is increased risk for breast tissue especially in the younger patients. As per legislation, justification is required and CTAC should only be used in situations that demonstrate sufficient net benefit.Single-photon emission CT (SPECT)/CT has become common place in clinical imaging, and a major role for CT is for the attenuation correction (AC) of SPECT data in myocardial perfusion imaging (MPI). 1,2 The benefits of CT attenuation correction (CTAC) in MPI are well known and many national and international professional organizations recommend its use to improve SPECT MPI diagnostic accuracy. 3,4 Associated with the CT acquisition is an additional radiation dose that is often considered to be low, yet very few articles quantify the dose and the associated risk.Effective dose is a useful figure that allows for a comparison between different tech...

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Section: Discussionmentioning

confidence: 99%

Comparison of effective dose and lifetime risk of cancer incidence of CT attenuation correction acquisitions and radiopharmaceutical administration for myocardial perfusion imaging

Tootell

Szczepura²,

Hogg³

2014

BJR

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“…For most applications, these settings can be kept to 100 kVp and 10 mAs. 21 The lowest dose CT acquisition mode uses a sequential ''prospective ECG-triggered axial scan.'' This acquisition mode acquires a single slab using a single rotation of the CT scanner followed by moving the table to the next acquisition position.…”

Section: Optimizing Attenuation Correction Transmission Scan Settingsmentioning

confidence: 99%

“…PET/CT systems employ a conventional multislice x-ray CT system capable of acquiring highresolution, diagnostic quality data and/or low-dose attenuation correction scans. 20 Radiation from CT-based attenuation systems can be as little as 0.3 mSv 21 to upwards of 8.5 mSv, 22 the latter dose being over twice the radiation dose from a 82 Rb perfusion examination. Minimizing the radiation dose means using appropriate protocols for cardiac PET/CT attenuation correction.…”

mentioning

confidence: 99%

Status of cardiovascular PET radiation exposure and strategies for reduction: An Information Statement from the Cardiovascular PET Task Force

Case

deKemp

Slomka

et al. 2017

Journal of Nuclear Cardiology

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Cardiovascular positron emission tomography (PET) imaging provides high-quality visual and quantitative myocardial perfusion and function images. In addition, cardiovascular PET can assess myocardial viability, myocardial inflammatory disorders such as cardiac sarcoid, and infections of implanted devices including pacemakers, ventricular assist devices, and prosthetic heart valves. As with all nuclear cardiology procedures, the benefits need to be considered in relation to the risks of exposure to radiation. When performed properly, these assessments can be obtained while simultaneously minimizing radiation exposure. The purpose of this information statement is to present current concepts to minimize patient and staff radiation exposure while ensuring high image quality.

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“…The simultaneous acquisition of a standard diagnostic CT scan with intravenous contrast agent is possible. PET images are visually evaluated to search for area of increased [ 18 [9]. To prevent misinterpretation of a positive scan due to early imaging after valve implantation, the ESC Guidelines recommend not to consider [ 18 F]FDG PET results in the 3-month period following prosthetic heart valve (PHV) implantation [5] (Table 1).…”

Section: Introductionmentioning

confidence: 99%

Radionuclide Imaging of Infective Endocarditis: State of Art and Future Perspective

Marchetta

Withofs

Erba

et al. 2017

Curr Cardiovasc Imaging Rep

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Purpose of Review Infectious endocarditis is a serious disease requiring rapid diagnosis and accurate risk stratification to offer the best therapeutic strategy. Infection of prosthetic valve (PV) and cardiovascular implantable electronic device (CIED) is increasing due to the ageing of the population and the growing number of implants. Foreign material infection remains clinically challenging given the limitation of ultrasound techniques in this context whereas the diagnosis must be precocious. Recent Findings 18 F-fluorodeoxyglucose positron emission tomography/computed tomography ([ 18 F]FDG PET/CT) and radiolabelled leukocytes single-photon emission computed tomography/computed tomography (SPECT/CT) are commonly used for this purpose.Summary In the present article, we summarized the available evidence for the use of nuclear imaging for the evaluation of infectious endocarditis.

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SNMMI/ASNC/SCCT Guideline for Cardiac SPECT/CT and PET/CT 1.0

Cited by 190 publications

References 129 publications

Comparison of effective dose and lifetime risk of cancer incidence of CT attenuation correction acquisitions and radiopharmaceutical administration for myocardial perfusion imaging

Comparison of effective dose and lifetime risk of cancer incidence of CT attenuation correction acquisitions and radiopharmaceutical administration for myocardial perfusion imaging

Status of cardiovascular PET radiation exposure and strategies for reduction: An Information Statement from the Cardiovascular PET Task Force

Radionuclide Imaging of Infective Endocarditis: State of Art and Future Perspective

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