SNF1-Related Protein Kinase 1 Activity Represses the Canonical Translational Machinery

Son, Seungmin; Im, Jong Hee; Song, Giha; Park, Sang Ryeol

doi:10.3390/plants11101359

Cited by 4 publications

(2 citation statements)

References 31 publications

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“…Remarkably, SnRK1-mediated eIF4E and eIFiso4E phosphorylation attenuates general translation (Bruns et al, 2019). Furthermore, SnRK1 activity represses canonical protein biosynthesis without significantly changing transcript levels and protein stability (Son et al, 2022). However, under submergence conditions, SnRK1-mediated eIFiso4G1 phosphorylation confers translational enhancement of specific mRNAs, including those of core hypoxia-response genes (Cho et al, 2019).…”

Section: Translation Mechanisms Regulated By Hypoxia In Plantsmentioning

confidence: 99%

Plant translational reprogramming for stress resilience

Son

Park²

2023

Front. Plant Sci.

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Organisms regulate gene expression to produce essential proteins for numerous biological processes, from growth and development to stress responses. Transcription and translation are the major processes of gene expression. Plants evolved various transcription factors and transcriptome reprogramming mechanisms to dramatically modulate transcription in response to environmental cues. However, even the genome-wide modulation of a gene’s transcripts will not have a meaningful effect if the transcripts are not properly biosynthesized into proteins. Therefore, protein translation must also be carefully controlled. Biotic and abiotic stresses threaten global crop production, and these stresses are seriously deteriorating due to climate change. Several studies have demonstrated improved plant resistance to various stresses through modulation of protein translation regulation, which requires a deep understanding of translational control in response to environmental stresses. Here, we highlight the translation mechanisms modulated by biotic, hypoxia, heat, and drought stresses, which are becoming more serious due to climate change. This review provides a strategy to improve stress tolerance in crops by modulating translational regulation.

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Section: Translation Mechanisms Regulated By Hypoxia In Plantsmentioning

confidence: 99%

Plant translational reprogramming for stress resilience

Son

Park²

2023

Front. Plant Sci.

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“…Under such conditions, the plant must balance energy expenditure to maintain homeostasis. Work [10] showed that activation of SnRK1, a key sensor of energy stress signalling, leads to reprogramming of the transcriptome and metabolism to adapt to such cellular energy crises and survive them. SnRK1 phosphorylates the 4G1 isoform (eIFiso4G1) of the eukaryotic translation initiation factor (eIFiso17G4), which leads to a higher translational efficiency of specific transcripts, including those induced by hypoxia during flooding.…”

Section: Signaling Pathways Start Of Changesmentioning

confidence: 99%

Regulation of Plant Translation under Abiotic Stress. A Molecular Orchestration

Suhorukova,

Sobolev,

Milovskaya

et al. 2023

Preprint

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Stress is one of the important factors affecting the growth and development of plants. In recent years, a large body of data on transcriptional changes in response to stress in plants has been obtained. Despite the fact that the important role of the regulation of translation in response to stress has been proven in plants, knowledge in this area remains extremely scarce. In this review, we focused on mRNA translation in the cytoplasm of higher plants. Most of the current research on the effects of translation has been done in yeast and mammalian systems. Translation factors and mechanisms are mostly conserved among eukaryotes; however, some differences are known to exist among plants. A comprehensive understanding of the complex apparatus of translation and its regulation in plants is required. In this work, we have tried to update modern ideas about the regulation of translation under conditions of abiotic stress.

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Thermal adaptation in plants: understanding the dynamics of translation factors and condensates

Lohmann,

Herzog,

Rosenzweig

et al. 2024

Journal of Experimental Botany

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Plants, as sessile organisms, face the imperative challenge of adjusting growth and development with ever-changing environmental conditions. Protein synthesis is the fundamental process enabling growth of all organisms. Since elevated temperature stress poses a substantial threat to protein stability and function, immediate adjustments of protein synthesis rates are necessary to circumvent accumulation of proteotoxic stress and ensure survival. This review provides an overview about the mechanisms that control translation upon high temperature stress in plants compared to yeast and metazoa by modifying components of the translation machinery. Recent research suggests also an important role for cytoplasmic biomolecular condensates, named stress granules in these processes. The current understanding on the role of stress granules in translational regulation and on the molecular processes associated with translation that might occur within stress granules will also be discussed.

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SNF1-Related Protein Kinase 1 Activity Represses the Canonical Translational Machinery

Cited by 4 publications

References 31 publications

Plant translational reprogramming for stress resilience

Plant translational reprogramming for stress resilience

Regulation of Plant Translation under Abiotic Stress. A Molecular Orchestration

Thermal adaptation in plants: understanding the dynamics of translation factors and condensates

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