Snake envenomation during pregnancy

Martinez, Denisse G; Osborne, Newton G.

doi:10.29328/journal.cjog.1001039

Cited by 3 publications

(3 citation statements)

References 11 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In addition, envenomation during pregnancy is associated with adverse maternal and foetal outcomes [ 4 ]. The coagulating agent in the toxin can reach the decidua-placental cleavage zone and may start a dissociation leading to placental abruption [ 8 ]. Similarly, placental abruption was suspected in our case as the patients developed abdominal pain and heavy vaginal bleeding.…”

Section: Discussionmentioning

confidence: 99%

Management of snake bite during third trimester of pregnancy with coagulopathy and delivery of a live baby in resource-limited setting in Nepal: a case report

Gupta

Bhandari

Anand

et al. 2022

Oxford Medical Case Reports

View full text Add to dashboard Cite

We reported a case of snakebite in an 18-year-old woman, Gravida 2 Para 1+0 in the third trimester of pregnancy who presented with pain and swelling over the left hand and forearm and vaginal spotting. The laboratory investigations revealed coagulopathy attributed to green pit viper envenomation. On the fourth day of admission, the patient developed sudden abdominal pain and massive per vaginal bleeding with haemorrhagic shock, most likely abruptio placentae. In Nepal, no anti-snake venom has been developed for green pit-viper. So, she was managed conservatively, including blood transfusion, and delivered a single live female baby without any foetal complications. The patient was discharged along with the baby after 8 days of hospitalization. This case demonstrated that vigilant observation and appropriate resuscitation with fluids and blood products could save mother and baby in pit viper envenomation cases in settings where specific anti-snake venom is unavailable.

show abstract

Section: Discussionmentioning

confidence: 99%

Management of snake bite during third trimester of pregnancy with coagulopathy and delivery of a live baby in resource-limited setting in Nepal: a case report

Gupta

Bhandari

Anand

et al. 2022

Oxford Medical Case Reports

View full text Add to dashboard Cite

show abstract

“…Foetal loss is more likely to occur early in the gestation period [ 21 , 44 ]. Abruptio placenta, especially in haemotoxic SBE, is the commonest cause of foetal loss [ 45 ]. Interestingly, the Brazilian study [ 21 ] showed no difference in severity or case fatality between pregnant and non-pregnant women of childbearing age.…”

Section: Pregnancymentioning

confidence: 99%

“…One review in 2010 reported a case fatality rate of 4.2% and 19.2% in pregnant women and neonates, respectively [ 22 ]. Mechanisms proposed to explain foetal deaths included anoxia secondary to maternal shock, abruptio placenta, venom-induced premature uterine contractions, and a direct venom effect on the foetus [ 45 ].…”

Section: Pregnancymentioning

confidence: 99%

Clinical Risk Factors Associated with Poor Outcomes in Snake Envenoming: A Narrative Review

Wood

2023

Toxins

View full text Add to dashboard Cite

Snakebite-related fatalities disproportionately affect populations in impoverished socio-economic regions, marked by limited access to adequate healthcare and constrained antivenom availability. Early medical intervention is pivotal in mitigating mortality and morbidity associated with snakebite envenoming (SBE). While clinical assessment remains fundamental in treating SBE, this review aims to spotlight objective parameters that could also affect outcomes. Selected studies that identify factors associated with poor outcomes are predominantly region-specific, single-site, and observational, yet collectively reveal similar findings. They consistently report factors such as treatment delays, susceptibility in vulnerable groups such as children and pregnant women, as well as various biochemical and haematological abnormalities. Acute kidney injury (AKI), low platelets, leucocytosis, abnormal coagulation, and elevated creatine kinase (CK) all show an association with poor outcomes. Furthermore, recognising rare and unusual SBE presentations such as adrenal insufficiency, severe hypertension, intracranial haemorrhage, acute angle closure glaucoma, and bowel ischaemia also has a bearing on outcomes. Despite the integration of these parameters into clinical decision tools and guidelines, the validation of this evidence is limited. This review underscores the imperative for high-quality, multi-centre studies aligned with consensus-driven Core Outcome Sets (COS) and Patient-Reported Outcome Measures (PROMS) to validate and strengthen the current evidence.

show abstract

Placental Abruption Following Snakebites Envenomation: A Case Report and Literature Review

Logbo-Akey¹,

M’bortche²,

Kambote³

et al. 2023

OJOG

View full text Add to dashboard Cite

Background: Snakebite envenomation in pregnancy is uncommon. It can lead to a poor outcome in both the mother and the fetus. We describe our approach to envenomation in pregnancy based on the currently available evidence. Case: We reported two case of snakebite in the third trimester of pregnancy having caused placental abruption with expelling a fresh still born baby and a live baby. In both cases, consumption coagulopathy occurred. managed by polyvalent anti-snake and blood transfusion. Their investigations became normal and they were discharged of hospitalization. Conclusion: Snakebite envenomation in pregnant is a maternal and fetal emergency. Treatment must be quick and well adapted.

show abstract

Snake envenomation during pregnancy

Cited by 3 publications

References 11 publications

Management of snake bite during third trimester of pregnancy with coagulopathy and delivery of a live baby in resource-limited setting in Nepal: a case report

Management of snake bite during third trimester of pregnancy with coagulopathy and delivery of a live baby in resource-limited setting in Nepal: a case report

Clinical Risk Factors Associated with Poor Outcomes in Snake Envenoming: A Narrative Review

Placental Abruption Following Snakebites Envenomation: A Case Report and Literature Review

Contact Info

Product

Resources

About