We are interested in the thin-film equation with zero-contact angle and quadratic mobility, modeling the spreading of a thin liquid film, driven by capillarity and limited by viscosity in conjunction with a Navier-slip condition at the substrate. This degenerate fourthorder parabolic equation has the contact line as a free boundary. From the analysis of the self-similar source-type solution, one expects that the solution is smooth only as a function of two variables (x, x β ) (where x denotes the distance from the contact line) with β = √ 13−1 4 ≈ 0.6514 irrational. Therefore, the well-posedness theory is more subtle than in case of linear mobility (coming from Darcy dynamics) or in case of the second -order counterpart (the porous medium equation).Here, we prove global existence and uniqueness for one-dimensional initial data that are close to traveling waves. The main ingredients are maximal regularity estimates in weighted L 2 -spaces for the linearized evolution, after suitable subtraction of a(t) + b(t)x β -terms.