Smooth Endoplasmic Reticulum in Rat Hepatocytes during Glycogen Deposition and Depletion

Structural Changes in Rat Hepatocytes following Ingestion of Sugar Solutions

“…Glycogen particles were dispersed throughout the cytosome and did not accumu late in masses. This concurs with the pattern of glycogen deposition in hepatocytes surrounding the terminal hepatic vein (ccntrilobular) [Cardell, 1977]. Some areas of the cisternae of rough endoplasmic reticulum were devoid of ribosomes and some membranous formations, devoid of ribosomes, were seen.…”

“…and embed ded in Tissue Prep (Fisher Scientific Co.). Sections of 5-8 pm were stained with alum haematoxylin and eosin [Cook, 1974. p | Cardell, 1977]. Upon remov al.…”

Liver Perfusion: an in Vitro Technique for the Study of Intracellular Protein Turnover and Its Regulation in Vivo

“…Ahlberg et al (1982) have observed that lysosomes in vitro continuously take up and degrade proteins from the medium, presumably by a process analogous to volume endocytosis. On the other hand, (Cardell, 1977), one might expect to see a progressive decline in microautophagic activity if indeed there is a connedtion between smooth ER and this process. The continued decrease in microautophagic activity with refeeding is equally obscure.…”

The membrane association among the rough- and smooth-surfaced endoplasmic reticulum and Golgi apparatus in rat hepatocytes at certain circadian stages.

“…2c). Cardell (1976) postulated that during the decrease in glycogen content of hepatocytes, sER occurs from the cisternal end of rER, which is accelerated under the condition of phenobarbital treatment. In the present study, the Fig.…”

“…The author (1981) clarified the relationship between ER and outer mitochondrial membranes through the tubular structure, which forms a bridge between the two organelles and whose incidence demonstrates a circadian change. A possibility of membrane transformation from rER to sER in rat hepatocytes has been suggested under normal and experimental conditions by several investigators (Staubli et al 1969;Cardell 1976). …”