Smoking, passive smoking and histological types in lung cancer in Hong Kong Chinese women

Lam, Tai Hing; Kung, I. T. M.; Wong, Chan‐Yuan; Lam, WK; Kleevens, J W; D, Saw; Hsu, C.; Seneviratne, Sanjeewa; Lam, S.; Lo, Kai

doi:10.1038/bjc.1987.264

Cited by 117 publications

(58 citation statements)

References 12 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…The above results in the study of female lung cancer and smoking status were quite similar to the reports in China and abroad (2,3,4). Smoking increase the risk of female lung cancer in Shenyang districts up to 2.5 times but the increase is still lower than that for males.…”

Section: Discussionsupporting

confidence: 78%

“…The results are quite different from that reported by Lam and Kung et al (3,5). Adenocarcinoma in our study was relatively less frequent but small cells carcinoma was more .…”

Section: Discussioncontrasting

confidence: 57%

“…The smoking rate of the controls in this series may be higher than that of general population. Although a number of studies indicated that females affected by passive smoking had a higher risk of lung cance (3,7,8), our study by type of lung cancer did not show this correlation. This is probably due to the relatively small sample size in this series.…”

Section: Discussioncontrasting

confidence: 52%

See 2 more Smart Citations

Female Lung Cancer and Smoking Habits

ZhongXing

Sasaki

et al. 1992

Journal of Epidemiology

View full text Add to dashboard Cite

Section: Discussionsupporting

confidence: 78%

“…The results are quite different from that reported by Lam and Kung et al (3,5). Adenocarcinoma in our study was relatively less frequent but small cells carcinoma was more .…”

Section: Discussioncontrasting

confidence: 57%

Section: Discussioncontrasting

confidence: 52%

See 1 more Smart Citation

Female Lung Cancer and Smoking Habits

ZhongXing

Sasaki

et al. 1992

Journal of Epidemiology

View full text Add to dashboard Cite

“…Studies based on general exposure to ETS produced similar results (6,7). Similarly, a large number of case-control studies conducted in several countries provided evidence of an increased risk for lung cancer associated with ETS exposure from the spouse, indicating an exposure-response relationship (8)(9)(10)(11)(12). The evidence for an association between lung cancer and childhood exposure to ETS is less consistent than that for exposure in adulthood.…”

Section: Introductionmentioning

confidence: 91%

Uptake of the Tobacco-Specific Lung Carcinogen 4-(Methylnitrosamino)-1-(3-pyridyl)-1-Butanone by Moldovan Children

Stepanov

Hecht

Duca

et al. 2006

Cancer Epidemiology, Biomarkers &Amp; Prevention

View full text Add to dashboard Cite

The evidence of an association between childhood exposure to environmental tobacco smoke (ETS) and an increased risk of lung cancer is inconsistent. However, taking into account the existing association between lung cancer and adulthood ETS exposure, it is plausible that children exposed to ETS also would be at risk of developing lung cancer later in life. In this study, we investigated the uptake by Moldovan children of the tobacco-specific lung carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) by measuring total 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL), the sum of the NNK metabolites, NNAL, and its Oglucuronide and N-glucuronide (NNAL-Glucs) in urine. We also measured urinary cotinine and its glucuronide (total cotinine). Total NNAL was detected in 69 of 80 samples, including those that were low in cotinine (<5 ng/mL). The mean F SD level of total NNAL (0.09 F 0.077 pmol/mL) was comparable with those observed in previous studies of children and adults exposed to ETS. Total NNAL correlated with total cotinine (r = 0.8, P < 0.0001). The mean F SD levels of total NNAL and total cotinine were higher in children who were exposed to ETS (0.1 F 0.08 and 109 F 126 pmol/mL, respectively) than in those who were classified as unexposed to ETS based on questionnaire data (0.049 F 0.016 pmol/mL and 0.043 F 0.040 nmol/mL). The results of this study for the first time show widespread and considerable uptake of nicotine and the tobacco-specific lung carcinogen NNK in Moldovan children. These results should be useful in heightening the awareness of the dangers of smoking and ETS exposure in this eastern European country. (Cancer Epidemiol Biomarkers Prev 2006;15(1):7 -11)

show abstract

“…Besides active smoking, environmental tobacco smoke (ETS) has been linked to excess risk of lung cancer in epidemiologic studies (11)(12)(13). However, the overall evidence indicates that this association is weak (in terms of relative risk) and varied widely according to the study design and the population under study (14,15).…”

Section: Introductionmentioning

confidence: 93%

Dose-Response Relationship between Cooking Fumes Exposures and Lung Cancer among Chinese Nonsmoking Women

et al. 2006

View full text Add to dashboard Cite

The high incidence of lung cancer among Chinese females, despite a low smoking prevalence, remains poorly explained. Cooking fume exposure during frying could be an important risk factor. We carried out a population-based case-control study in Hong Kong. Cases were Chinese female nonsmokers with newly diagnosed primary lung cancer. Controls were female nonsmokers randomly sampled from the community, frequency matched by age groups. Face-to-face interviews were conducted using a standardized questionnaire. The ''total cooking dish-years,'' categorized by increments of 50, was used as a surrogate of cooking fumes exposure. Multiple unconditional logistic regression was used to estimate the odds ratios (OR) for different levels of exposure after adjusting for various potential confounding factors. We interviewed 200 cases and 285 controls. The ORs of lung cancer across increasing levels of cooking dish-years were 1, 1.17, 1.92, 2.26, and 6.15. After adjusting for age and other potential confounding factors, the increasing trend of ORs with increasing exposure categories became clearer, being 1, 1.31, 4.12, 4.68, and 34. The OR of lung cancer was highest for deep-frying (2.56 per 10 dish-years) followed by that of frying (1.47), and stir-frying had the lowest OR (1.12) among the three methods. Cumulative exposure to cooking by means of any form of frying could increase the risk of lung cancer in Hong Kong nonsmoking women. Practical means to reduce exposures to cooking fumes should be given top priority in future research. (Cancer Res 2006; 66(9): 4961-7)

show abstract

Smoking, passive smoking and histological types in lung cancer in Hong Kong Chinese women

Cited by 117 publications

References 12 publications

Female Lung Cancer and Smoking Habits

Female Lung Cancer and Smoking Habits

Uptake of the Tobacco-Specific Lung Carcinogen 4-(Methylnitrosamino)-1-(3-pyridyl)-1-Butanone by Moldovan Children

Dose-Response Relationship between Cooking Fumes Exposures and Lung Cancer among Chinese Nonsmoking Women

Contact Info

Product

Resources

About