Smoking as a Preventable Risk Factor for Rheumatoid Arthritis: Rationale for Smoking Cessation Treatment in Patients with Rheumatoid Arthritis

Roh, Sungwon

doi:10.4078/jrd.2019.26.1.12

Cited by 6 publications

(4 citation statements)

References 67 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…According to research in Israel avoiding offending diet and intake of proper diet may affect the flares of PR. Smoking can also trigger the process of Citrullination by affecting the immune reactions of the HLA Gene [39]. Most of the case study reports that the onset of PR frequently begins in the late afternoon and early morning [40,41].…”

Section: Environmental Factorsmentioning

confidence: 99%

Palindromic Rheumatism: Biology and Treatment Options

Noor¹,

Ishaq²,

Fatima³

et al. 2021

Genetic Variation

View full text Add to dashboard Cite

Palindromic rheumatism is a syndrome characterized by recurrent, self-resolving, and inflammatory attacks in and around the joints that have long recognized association with rheumatoid arthritis. PR attacks mostly start in small joints i.e. knees, shoulder, and small joints of the hand. Whether PR should be considered as a single disease or prodrome of RA remains a thought-provoking question. Multiple genetic and environmental factors contribute to the development of PR. Many studies have explained the relationship between a high concentration of Anti-CCP antibodies and PR. Potential benefits of Gold therapy have been recognized in literature but still, there are some questions about toxicity and efficacy that need further considerations. In addition to that anti-malarial drugs, Abatacept, Tofacitinib, and Rituximab showed the variable result in different patients and needed further study to validate their medical use. Moreover, yarrow, oat, colchicum, dill, fennel, wild rue, bitter melon, willow, garlic, and burdock seem suitable candidates to treat rheumatoid although their use in PR is still not reported. Additional experimental researches on these drugs lead to an increase in our knowledge to fight against PR in the future using novel therapeutic approaches. We have attempted to cover this topic in a chapter form to provide a comprehensive view and hope that it will serve as a reference for clinicians who treat patients with PR.

show abstract

Section: Environmental Factorsmentioning

confidence: 99%

Palindromic Rheumatism: Biology and Treatment Options

Noor¹,

Ishaq²,

Fatima³

et al. 2021

Genetic Variation

View full text Add to dashboard Cite

show abstract

“…Physiopathologically, there is growing evidence that RA begins in the lung with active citrullination of vimentin peptides induced by tobacco exposure ( 2 , 3 ). Similarly, epidemiological data showed that in a global RA population, most of the patients were presenting a tobacco abuse history (former smokers or ex-smokers) ( 4 ).…”

Section: Introductionmentioning

confidence: 99%

Airflow obstruction as a marker of adverse prognosis in rheumatoid arthritis

Guiot

Henket²,

Ernst³

et al. 2023

Front. Med.

View full text Add to dashboard Cite

ObjectivesIn our study, we explored the specific subgroup of patients with rheumatoid arthritis (RA) suffering from obstructive lung disease (OLD) and its impact on morbi-mortality.MethodsOur retrospective study included 309 patients suffering from RA with either obstructive (O-RA) or non-obstructive patterns (non-O-RA). OLD was defined based on the Tiffeneau index at the first available pulmonary functional test (PFT). Survival was then calculated and represented by a Kaplan–Meier curve. The comparison between the populations considered was performed by the Log-Rank test.ResultsOut of the 309 RA patients, 102 (33%) had airway obstruction. The overall survival time was significantly lower in the O-RA group than in the non-O-RA group (n = 207) (p < 0.001). The median survival time was 11.75 years in the O-RA group and higher than 16 years in the non-O-RA group. Multivariate analysis identified OLD as an independent risk factor for mortality (HR 2.20; 95% CI 1.21–4.00, p < 0.01).ConclusionAirway obstruction can be an independent risk factor of mortality in RA and should be considered as an early marker of poor prognosis. Further prospective longitudinal studies are required in order to determine the best clinical management for O-RA patients.

show abstract

“…Furthermore, evidence suggest that half of the patients with RA are current smokers at the time of disease onset [ 11 ] and up to 26% continue to smoke despite the risk for increased RA complications, hospitalizations due to cardiovascular disease and respiratory tract infections, osteoporosis, and poor response to treatment [ 13 , 14 ]. Factors associated with smoking persistence in patients with RA are thought to be a combination of biological, psychological and social factors including managing RA pain, using smoking as a coping strategy, behavior carried from adolescence, and/or limited knowledge about the effects of smoking on the disease [ 15 ].…”

Section: Introductionmentioning

confidence: 99%

A systematic review with meta-analysis of the effects of smoking cessation strategies in patients with rheumatoid arthritis

López-Olivo

Sharma²,

Singh³

et al. 2022

PLoS ONE

View full text Add to dashboard Cite

Objective Smoking rates among patients with rheumatoid arthritis (RA) exceed those in the general population. This study identified smoking cessation strategies used in patients with RA and synthesized data on their effects. Methods We conducted a systematic review of studies that reported effects of interventions for smoking cessation in patients with RA. We searched 5 electronic databases until March 2022. Screening, quality appraisal, and data collection were done independently by 2 reviewers. Results We included 18 studies reporting interventions for patients or providers: 14 evaluated strategies for patients (5 education on cardiovascular risk factors including smoking, 3 educational interventions on smoking cessation alone, 3 education with nicotine replacement and counseling, and 1 study each: education with nicotine replacement, counseling sessions alone, and a social marketing campaign). Smoking cessation rates ranged from 4% (95% CI: 2%-6%, 24 to 48 weeks) for cardiovascular risk education to 43% (95% CI: 21%-67%, 104 weeks) for counseling sessions alone. The pooled cessation rate for all interventions was 22% (95% CI: 8%-41%, 4 weeks to 104 weeks; 9 studies). Four interventions trained providers to ascertain smoking status and provide referrals for smoking cessation. The pooled rates of referrals to quit services increased from 5% in pre-implementation populations to 70% in post-implementation populations. Conclusion Studies varied in patient characteristics, the interventions used, and their implementation structure. Only 3 studies were controlled clinical trials. Additional controlled studies are needed to determine best practices for smoking cessation for patients with RA.

show abstract

Smoking as a Preventable Risk Factor for Rheumatoid Arthritis: Rationale for Smoking Cessation Treatment in Patients with Rheumatoid Arthritis

Cited by 6 publications

References 67 publications

Palindromic Rheumatism: Biology and Treatment Options

Palindromic Rheumatism: Biology and Treatment Options

Airflow obstruction as a marker of adverse prognosis in rheumatoid arthritis

A systematic review with meta-analysis of the effects of smoking cessation strategies in patients with rheumatoid arthritis

Contact Info

Product

Resources

About