Smoking and degenerative spinal disease: A systematic review

Rajesh, Niharika; Moudgil-Joshi, Jigishaa; Kaliaperumal, Chandrasekaran

doi:10.1016/j.bas.2022.100916

Cited by 8 publications

(4 citation statements)

References 64 publications

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“…We also identified that smoking was more common in both groups compared to general population averages, with 50 % of the DCM group and 53 % of the DTM group having never smoked in comparison to 57 % of 55-64 years olds in the general population [29]. This supports the potential association between smoking and degenerative spinal disease [30][31][32].…”

Section: Discussionsupporting

confidence: 65%

A single centre service evaluation of degenerative cervical and thoracic myelopathy

Rujeedawa,

Mowforth,

Brannigan

et al. 2023

Journal of Clinical Neuroscience

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Section: Discussionsupporting

confidence: 65%

A single centre service evaluation of degenerative cervical and thoracic myelopathy

Rujeedawa,

Mowforth,

Brannigan

et al. 2023

Journal of Clinical Neuroscience

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“…Aging: The aging process itself is a significant risk factor for both vascular dysfunction and degenerative diseases [97,98]. As people age, their blood vessels naturally undergo structural and functional changes, becoming less elastic and more susceptible to damage [99]. This contributes to conditions like arterial stiffness and an increased risk of atherosclerosis, which can affect both the heart and other organs.…”

Section: Common Risk Factors That Affect Vascular System and Degenera...mentioning

confidence: 99%

“…iii. Smoking: Smoking is a major risk factor for vascular dysfunction and degenerative diseases [99,100]. It constricts blood vessels, increases oxidative stress, increases blood coagulability, reduces oxygen delivery to tissues, and promotes the development of atherosclerosis.…”

Section: Common Risk Factors That Affect Vascular System and Degenera...mentioning

confidence: 99%

The Role of the Vascular System in Degenerative Diseases: Mechanisms and Implications

Sheikh,

Yano,

Tabassum

et al. 2024

IJMS

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Degenerative diseases, encompassing a wide range of conditions affecting various organ systems, pose significant challenges to global healthcare systems. This comprehensive review explores the intricate interplay between the vascular system and degenerative diseases, shedding light on the underlying mechanisms and profound implications for disease progression and management. The pivotal role of the vascular system in maintaining tissue homeostasis is highlighted, as it serves as the conduit for oxygen, nutrients, and immune cells to vital organs and tissues. Due to the vital role of the vascular system in maintaining homeostasis, its dysfunction, characterized by impaired blood flow, endothelial dysfunction, and vascular inflammation, emerges as a common denominator of degenerative diseases across multiple systems. In the nervous system, we explored the influence of vascular factors on neurodegenerative diseases such as Alzheimer’s and Parkinson’s, emphasizing the critical role of cerebral blood flow regulation and the blood–brain barrier. Within the kidney system, the intricate relationship between vascular health and chronic kidney disease is scrutinized, unraveling the mechanisms by which hypertension and other vascular factors contribute to renal dysfunction. Throughout this review, we emphasize the clinical significance of understanding vascular involvement in degenerative diseases and potential therapeutic interventions targeting vascular health, highlighting emerging treatments and prevention strategies. In conclusion, a profound appreciation of the role of the vascular system in degenerative diseases is essential for advancing our understanding of degenerative disease pathogenesis and developing innovative approaches for prevention and treatment. This review provides a comprehensive foundation for researchers, clinicians, and policymakers seeking to address the intricate relationship between vascular health and degenerative diseases in pursuit of improved patient outcomes and enhanced public health.

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“…Паління вважається прогностичним чинником рГМД [4,24,34,[36][37][38]. Точний механізм впливу тютюнопаління на розвиток рГМД, дотепер не зовсім зрозумілий.…”

Section: чинники ризику ргмд після первинної дискектоміїunclassified

Epidemiologicalrisk Factors of Recurrence of Lumbar Intervertebral Disc Herniation After Primary Discectomy (Literature Review)

Radchenko,

Piontkovskyi,

Kolesnichenko

et al. 2024

OTP

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Primary discectomy for a lumbar intervertebral disc herniated (LDH) is usually accompanied by a rapid regression of clinical symptoms, however, in 5–15 % of cases, an X-ray positive recurrence of the hernia with corresponding orthopedic disorders is registered, which leads to repeated surgical intervention. Objective. Determination of risk factors for recurrence of LDH and their frequency under the conditions of various methods of primary discectomy based on a scientific analysis of the relevant literature. Methods. The material of the research is articles containing the definition of risk factors for the recurrence of a LDH after primary discectomy, for the period 2013–2023 in PubMed, Google Scholar, Medline databases using medical subject headings and keywords «recurrent lumbar disc herniation, surgical interventions, percutaneous endoscopic lumbar discectomy, microdiscectomy, laminectomy, discectomy, spondylodesis». The research method is a systematic review of relevant literature sources. Results. Early and long-term results of primary discectomy for intervertebral disc herniation using decompression (open discectomy, microendoscopic discectomy, percutaneous discectomy, laminectomy, minidiscectomy, endoscopic discectomy) and decompression-stabilization (discectomy combined with spondylodesis) techniques are traced in the literature. The most successful were: 1 year after the operation — endoscopic discectomy (12.4 % of reoperations) and spondylodesis (11.8 %); 10 years after the operation — laminectomy (14 %) and spondylodesis (10 %). The highest rates of revision discectomy: 1 year after the operation — laminectomy (18.6 %); 10 years after surgery — open discectomy and endoscopic discectomy — 16 % each. Conclusions. Recurrent intervertebral disc herniation is an early complication of primary discectomy, the frequency of which varies depending on the surgical technique and the timing of the postoperative period. The most reliable risk factors are male gender, age younger than 50 years, diabetes mellitus, and smoking.

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Smoking and degenerative spinal disease: A systematic review

Cited by 8 publications

References 64 publications

A single centre service evaluation of degenerative cervical and thoracic myelopathy

A single centre service evaluation of degenerative cervical and thoracic myelopathy

The Role of the Vascular System in Degenerative Diseases: Mechanisms and Implications

Epidemiologicalrisk Factors of Recurrence of Lumbar Intervertebral Disc Herniation After Primary Discectomy (Literature Review)

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