Smoking and chronic pain

Silva, Joel D'; Devadiga, Sumana; Dengody, Prasanna Kumar; Chalathadka, Mahabaleshwar; Bhoj, Mimansa; Jain, Vaibhav

doi:10.4103/2394-2010.150794

Cited by 3 publications

(3 citation statements)

References 5 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…32 This relationship is complex and is likely an interaction of biological, psychological, and social factors. 33 Additionally, in our study, open fractures were at higher risk of developing pain interference. This association is likely a reflection of the increased severity of injury and complicated recovery of those with open fractures over closed fractures.…”

Section: Discussionmentioning

confidence: 45%

Patient coping and expectations about recovery predict the development of chronic post-surgical pain after traumatic tibial fracture repair

Khan

Devereaux

LeManach

et al. 2016

British Journal of Anaesthesia

View full text Add to dashboard Cite

Background: The association of patient expectations about recovery with the development of chronic post-surgical pain (CPSP) is uncertain. Methods: Three hundred and fifty-nine patients enrolled in the SPRINT trial completed the Somatic Preoccupation and Coping (SPOC) questionnaire six weeks after a traumatic tibial fracture repair. The SPOC questionnaire measures patients' somatic complaints, coping, and optimism for recovery. Using adjusted models, we explored the association of SPOC scores with ≥ mild CPSP and ≥ moderate pain interference with activity at one yr after surgery. Results: Of 267 tibial fracture patients with data available for analysis, 147 (55.1%) reported CPSP at one yr. The incidence of CPSP was 37.6% among those with low (≤40) SPOC scores, 54.1% among those with intermediate (41-80) scores, and 81.7% among those with high (>80) scores. Addition of SPOC scores to an adjusted regression model to predict CPSP improved the c-statistic from 0.61 (95% CI 0.55-0.68) to 0.70 (95% CI 0.64-0.76, P=0.005 for the difference) and found the greatest risk was associated with high SPOC scores (OR 6.56,. Similarly, an adjusted regression model to predict pain interference with function at one yr (c-statistic 0.77, 95% CI 0.71-0.83) found the greatest risk for those with high SPOC scores (OR 10.10,. Conclusions: Patient's coping and expectations of recovery, as measured by the SPOC questionnaire, is an independent predictor of CPSP and pain interference one yr after traumatic tibial fracture. Future studies should explore whether these beliefs can be modified, and if doing so improves prognosis. Clinical trial registration: NCT 00038129

show abstract

Section: Discussionmentioning

confidence: 45%

Patient coping and expectations about recovery predict the development of chronic post-surgical pain after traumatic tibial fracture repair

Khan

Devereaux

LeManach

et al. 2016

British Journal of Anaesthesia

View full text Add to dashboard Cite

show abstract

“…14 However, nicotine itself has been reported as having analgesic properties. 8,9 There is emerging evidence on the acute analgesic effects of nicotine through the possible activation of nicotinic acetylcholine receptors distributed through the central and peripheral nervous systems. 9 Further, previous studies showed that people with chronic pain perceive smoking as a way to cope with pain and distress, and have concerns that abstinence would result in worsening of their pain.…”

Section: Discussionmentioning

confidence: 99%

“…[4][5][6] There are some possible mechanisms to explain the association between smoking and chronic pain conditions, but the most common may be related to the malnutrition of cells by carboxy-hemoglobin-induced anoxia and increased sensitivity of pain receptors in the brain. [7][8][9] There is evidence that those with chronic pain who are smokers present with more severe symptoms, have poorer treatment outcomes, and more symptoms of depression compared to non-smokers. [10][11][12] As such, smoking cessation has been suggested as a potentially important treatment target in people with chronic pain.…”

Section: Introductionmentioning

confidence: 99%

Interventions Targeting Smoking Cessation for Patients With Chronic Pain: An Evidence Synthesis

Saragiotto

Kamper

Hodder

et al. 2018

Nicotine &Amp; Tobacco Research

View full text Add to dashboard Cite

Introduction: Smoking is a risk factor for chronic pain conditions. Epidemiological evidence suggests that smoking cessation may be an important treatment target in people with chronic pain. The aim of this study was to examine the effectiveness of smoking cessation interventions in people with chronic pain. Methods: We systematically searched for clinical trials investigating the effectiveness of smoking cessation interventions for people with chronic pain, compared to any control comparator. Primary outcomes were pain and physical function. Secondary outcomes were smoking status, quality of life, psychological and cognitive function, and adverse events. We assessed risk of bias using the Cochrane Risk of Bias criteria, and the quality of evidence with GRADE. Results: Searches retrieved 3,845 records and identified two trials for inclusion (total n=99 participants). There was low quality evidence of no effect of smoking cessation programs on pain and very low quality evidence of no effect on function at short term follow-up. There was conflicting evidence on the effect of smoking cessation interventions for changing the smoking status, and number of cigarettes consumed per day. There was no effect on depression and anxiety. Conclusion: Current evidence does not indicate clinically important effects of smoking cessation interventions in people with chronic pain. There is a need for high quality trials in this area. Implications: Our review highlights an important evidence gap. We found only two studies investigating smoking cessation programs for chronic pain conditions providing very low to low quality evidence.

show abstract

Effects of electroacupuncture on pain sensation in a rat model of hyperalgesia with nicotine dependence

2022

View full text Add to dashboard Cite

Smoking and chronic pain

Cited by 3 publications

References 5 publications

Patient coping and expectations about recovery predict the development of chronic post-surgical pain after traumatic tibial fracture repair

Patient coping and expectations about recovery predict the development of chronic post-surgical pain after traumatic tibial fracture repair

Interventions Targeting Smoking Cessation for Patients With Chronic Pain: An Evidence Synthesis

Effects of electroacupuncture on pain sensation in a rat model of hyperalgesia with nicotine dependence

Contact Info

Product

Resources

About