Smoking and asthma in adults

Piipari, Ritva; Jaakkola, Jouni J. K.; Jaakkola, Niina; Jaakkola, Maritta S.

doi:10.1183/09031936.04.00116903

Cited by 152 publications

(84 citation statements)

References 28 publications

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“…The risk of developing asthma was significantly higher among current smokers and among exsmokers compared with those who have never smoked (adjusted odds ratio [OR], 1.33 and 1.49, respectively) in an investigation by Piipari et al 15 Their results support the hypothesis that smoking causes asthma in adulthood. In addition, they found that women may be more susceptible to the adverse effects of smoking.…”

Section: Risk Of Asthma Development From Primary Smokingsupporting

confidence: 73%

Smoking and Asthma

Stapleton

Howard-Thompson²,

George³

et al. 2011

The Journal of the American Board of Family Medicine

139

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Background:The purpose of this review is to describe the current understanding of the prevalence and adverse effects of cigarette smoking and secondhand smoke (SHS) in asthmatics in terms of patient outcomes and response to inhaled corticosteroids.Methods: We searched the English biomedical literature via PubMed, Embase, and Scopus using the terms "smoking and asthma," "secondhand smoke and asthma," "environmental tobacco smoke and asthma," and "smoking/secondhand smoke and corticosteroids." We also reviewed reference lists of identified articles for relevant citations.Results: In asthmatic patients who smoke, disease control is poorer than in asthmatic nonsmokers. Of all forms of SHS, maternal exposure seems to have the largest impact on asthma by increasing the frequency and severity of the disease and decreasing lung function. Asthmatic children exposed to multiple household smokers face an increased risk for respiratory illness-related absences from school, and these effects persist during adolescence but weaken during adulthood. Airway mucosal permeability is increased in smokers, which could lead to increased clearance of inhaled corticosteroids from the airways. Smokers also have decreased histone deacetylase activity, which is necessary for corticosteroids to fully suppress cytokine production, and can lead to corticosteroid resistance.

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Section: Risk Of Asthma Development From Primary Smokingsupporting

confidence: 73%

Smoking and Asthma

Stapleton

Howard-Thompson²,

George³

et al. 2011

The Journal of the American Board of Family Medicine

139

View full text Add to dashboard Cite

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“…Various studies have suggested that exposure to tobacco smoke can also increase the risk of developing asthma (56,59,(64)(65)(66)(67)(68). Several studies have found that exposure to tobacco smoke can increase the frequency and severity of asthmatic attacks (69)(70)(71), but some fail to link tobacco smoking to onset of asthma in adults (72,73).…”

Section: Introductionmentioning

confidence: 99%

Effect of Indoor Air Pollution from Biomass and Solid Fuel Combustion on Prevalence of Self-Reported Asthma among Adult Men and Women in India: Findings from a Nationwide Large-Scale Cross-Sectional Survey

Agrawal

2012

Journal of Asthma

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Objectives-Increasing prevalence of asthma in developing countries has been a significant challenge for public health in recent decades. A number of studies have suggested that ambient air pollution can trigger asthma attacks. Biomass and solid fuels are a major source of indoor air pollution, but in developing countries the health effects of indoor air pollution are poorly understood. In this study we examined the effect of cooking smoke produced by biomass and solid fuel combustion on the reported prevalence of asthma among adult men and women in India.Methods-The analysis is based on 99,574 women and 56,742 men aged between 20 and 49 years included in India's third National Family Health Survey conducted in [2005][2006]. Effects of exposure to cooking smoke, determined by the type of fuel used for cooking such as biomass and solid fuels versus cleaner fuels, on the reported prevalence of asthma were estimated using multivariate logistic regression. Since the effects of cooking smoke are likely to be confounded with effects of tobacco smoking, age, and other such factors, the analysis was carried out after statistically controlling for such factors.Results-The results indicate that adult women living in households using biomass and solid fuels have a significantly higher risk of asthma than those living in households using cleaner fuels (OR: 1.26; 95%CI: 1.06-1.49; p = .010), even after controlling for the effects of a number of potentially confounding factors. Interestingly, this effect was not found among men (OR: 0.98; 95%CI: 0.77-1.24; p = .846). However, tobacco smoking was associated with higher asthma prevalence among both women (OR: 1.72; 95%CI: 1.34-2.21; p < .0001) and men (OR: 1.35; 95%CI: 1.49-2.25; p < .0001). Combined effects of biomass and solid fuel use and tobacco smoke on the risk of asthma were greater and more significant in women (OR: 2.16; 95%CI: 1.58-2.94; p < .0001) than they were in men (OR: 1.34; 95%CI: 1.04-1.72; p = .024). Conclusions-The Europe PMC Funders Group

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“…1 5-9 The association between active smoking and incident asthma was observed in men only in one study, 1 and in women only in some other studies. [6][7][8] There are also contradictory results for the association between smoking and asthma risk from case-control studies [10][11][12] and cross-sectional studies. 13 14 Case-control and crosssectional study design cannot tell if smoking causes asthma or if asthma patients are less likely to start smoking or more likely to quit smoking.…”

Section: Introductionmentioning

confidence: 99%