Smear grading and the Mantoux skin test can be used to predict sputum smear conversion in patients suffering from tuberculosis

Saffari, Mahmood; Jolandimi, Hadis Alizadeh; Sehat, Mojtaba; Nejad, Nastarn Vali; Hedayati, Mehrdad; Zamani, Mahbobeh; Ghasemi, Ali

doi:10.3205/dgkh000297

Cited by 2 publications

(1 citation statement)

References 33 publications

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“…Therefore, there seems to be a relation between the degree of smear and the presence of cavity. In the study of M. Saffari et al (2017), with the increase in the degree of smear (+1, +2, +3, or +4 ), the frequency of CT scan findings including cavitation also increased significantly, so that the frequency of cavitation cases in degrees +1, +2, +3, and +4 was 33%, 68%, 94% and 100% respectively [16]. In the study of Penn-Nicholson A. et al ( 2019) with the increasing of the degree of smear, cavitation also increased significantly [15].…”

Section: Discussionmentioning

confidence: 99%

Sputum smear positivity grade and chest X-ray findings in tuberculosis: a cross-sectional study

Behzadmehr¹,

Nejadkehkha²

2022

Russian Journal of Infection and Immunity

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Despite many advances in the diagnosis, screening, and rapid treatment of tuberculosis, it is still a public health concern in the world. Due to the importance of this issue in diagnosis and reduction of transmission of infection and treatment of the disease especially where this study is conducted due to the high prevalence of tuberculosis, this study was done to determine The relationship between sputum smear positivity grade and chest X-ray findings in pulmonary tuberculosis patients in a hospital in southeast of Iran. This cross-sectional study was performed on all patients with pulmonary TB referencing the health centers in Zabol city, southeast of Iran from 1 January 2015 to 30 December 2020. Sputum smear and radiographic findings of the chest X-ray were evaluated. Data was collected using a form of information and finally analyzed by SPSS 22. Out of 101 patients examined in the present study, 71 were women and 30 were men. The mean age of the patients was 62.68 ± 13.61 years. The frequency of opacity in patients with grades 1, 2, and 3 was 71.4, 78.5, and 76.5%, respectively. Frequency of cavitation in patients with Grade 1, 2 and 3 was 11.5%, 28.5% and 52.9% respectively (P value 0.001). The frequency of reticulonodular presentations in patients with grade 1, 2, and 3 was 24.2, 7.1, and 0%, respectively. In general, the results of this study showed that, with increasing grading of smears (1+, 2+, and 3+), the frequency of cavitation presentation increased significantly and the frequency of reticulonodular presentations decreased significantly. In general, the results of this study showed that, with increasing grading of smears (, the frequency of Cavitation presentation increased significantly and the frequency of reticulonodular presentations decreased significantly. The findings of the present study can help physicians better diagnose TB.

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Section: Discussionmentioning

confidence: 99%

Sputum smear positivity grade and chest X-ray findings in tuberculosis: a cross-sectional study

Behzadmehr¹,

Nejadkehkha²

2022

Russian Journal of Infection and Immunity

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Determinants of sputum smear nonconversion in smear-positive pulmonary tuberculosis patients in Suriname, 2010 – 2015

Commiesie¹,

Stijnberg²,

Marín

et al. 2019

Revista Panamericana De Salud Pública

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Objective. To identify factors associated with sputum smear nonconversion in patients with pulmonary tuberculosis (PTB) in Suriname. Methods. A case-control study was conducted using routinely-collected surveillance data of PTB cases reported in January 2010 – December 2015 and recorded in the database of the National Tuberculosis Program of Suriname. Cases were smear-positive PTB patients whose sputum results were negative 2 months after treatment initiation. Controls were the smear-positive PTB patients whose sputum results were negative in the same timeframe. Multivariate logistic regression analysis was used to examine associations between potential risk factors and smear conversion. Results. The two age groups ≥ 35 years (35 – 54 years, AOR: 2.7, 95%CI: 1.2 – 6.1; and 55+ years, AOR: 2.5, 95%CI: 1.1 – 5.9) and high bacillary load at baseline (AOR 2.34, 95%CI: 1.2 – 4.8) were significantly associated with delayed smear conversion. Conclusion. The National TB program of Suriname should develop strategies to address patients at higher risk for delayed smear conversion to prevent further spreading and unfavorable treatment outcomes. To better inform decision-making and future studies, the NTP should expand its data collection to include all risk factors for delayed smear conversion.

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Smear grading and the Mantoux skin test can be used to predict sputum smear conversion in patients suffering from tuberculosis

Cited by 2 publications

References 33 publications

Sputum smear positivity grade and chest X-ray findings in tuberculosis: a cross-sectional study

Sputum smear positivity grade and chest X-ray findings in tuberculosis: a cross-sectional study

Determinants of sputum smear nonconversion in smear-positive pulmonary tuberculosis patients in Suriname, 2010 – 2015

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